Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.
Palmitoyl thio-PC
目录号: GC44549纯度: >98.00%
A chromogenic substrate for PLA2
Cas No.: 113881-60-0
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 1mg | ¥1,740.00 | 现货 | 1 | |
| 5mg | ¥7,746.00 | 现货 | 1 | |
| 10mg | ¥13,768.00 | 现货 | 1 |
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Nature641, 529–536 (2025)
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Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
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Cell Research35, 97–116 (2025)
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Cell Research33, 273–287 (2023)
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产品描述 Description
产品文档 Product Documents
Purity:>98.00%Appearance:A solid
化学性质Chemical Properties
CAS 号
113881-60-0
SMILES
CCCCCCCCCCCCCCCC(OC[C@@H](SC(CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
分子式
C40H80NO7PS
分子量
750.1 g/mol
溶解性
Ethanol: 50 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol
