Orcinol is a polyketide synthase-derived phenol that has been found in F. graminearum and has diverse biological activities.1,2,3 It scavenges DPPH radicals (IC50 = 2.93 mM).2 Orcinol (2.5 and 5 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.3 It has also been used in the colorimetric detection of carbohydrates.4,5
1.J?rgensen, S.H., Frandsen, R.J.N., Nielsen, K.F., et al.Fusarium graminearum PKS14 is involved in orsellinic acid and orcinol synthesisFungal Genet. Biol.7024-31(2014) 2.Lopes, T.I.B., Coelho, R.H., Toshida, N.C., et al.Radical-scavenging activity of orsellinatesChem. Pharm. Bull. (Tokyo)56(11)1551-1554(2008) 3.Wang, X., Li, G., Li, P., et al.Anxiolytic effects of orcinol glucoside and orcinol monohydrate in micePharm. Biol.53(6)876-881(2015) 4.DeGrandis, S., Law, H., Brunton, J., et al.Globotetraosylceramide is recognized by the pig edema disease toxinJ. Biol. Chem.264(21)12520-12525(1989) 5.Bruckner, J.Estimation of monosaccharides by the orcinol-sulphuric acid reactionBiochem. J.60(2)200-205(1955)