D panthenol (Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2].
[1] Zakaria MM, et al. J Pak Med Assoc. 2011, 61(9):889-92. [2] Heise R, et al. Skin Pharmacol Physiol. 2012, 25(5):241-8.
















