O-Desmethylangolensin (O-DMA) is a phytoestrogen and an active metabolite of daidzein .1 It is formed from daidzein by gut microbiota. O-DMA (2.5-50 ?M) is cytotoxic to MDA-MB-231 cells.2
1.Frankenfeld, C.L.O-desmethylangolensin: The importance of equol's lesser known cousin to human healthAdv. Nutr.2(4)317-324(2011) 2.Magee, P.J., McGlynn, H., and Rowland, I.R.Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitroCancer Lett.208(1)35-41(2004)