GlpBio

Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human)

目录号: GC31154纯度: >98%同义词: Neuropeptide Y (13-36), human
COASDSData Sheet

Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) 是一种选择性神经肽 Y2 受体激动剂。

Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human)
Cas No.: 122341-40-6
规格价格库存数量操作
1mg¥990.00现货
1
5mg¥2,880.00现货
1
10mg¥4,320.00现货
1
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产品描述 Description

Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.

Intraventricular injections of the Y2 neuropeptide Y receptor agonist porcine Neuropeptide Y (13-36) (25-3000 pM) produces a dose-dependent increase (up to 14%; ED50=0.3 nM for overall effects and 0.97 nM for the peak effects) in mean arterial blood pressure in the awake, unrestrains male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].

[1]. Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8.

实验参考方法 Experimental Reference Method

Animal experiment:

Rats[1]Neuropeptide Y (13-36) dissolved in 30 μL mock cerebrospinal fluid (CSF), or CSF alone, is injected (30/μL/3 min) by means of an automatic micro-injection pump into the lateral ventricle of freely moving, unrestrained male rats. Five doses of Neuropeptide Y (13-36) (25, 75, 750, 1250, 3000 pM) are injected in order to evaluate possible dose-dependent effects and the effects are compared with the CSF group. A threshold dose of Neuropeptide Y (13-36) is also injected together with a dose of Neuropeptide Y (1-36) (75 pM), close to the ED50 value for its overall vasodepressor action in awake rats[1].

References:

[1]. Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
122341-40-6
同义词
Neuropeptide Y (13-36), human
SMILES
Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
分子式
C134H207N41O36S
分子量
3000.4 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol