ND-322 drochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 drochloride reduces melanoma tumor growth and delays metastatic dissemination.
References:
[1]. Gooyit M, et, al. Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54(19):6676-90. [2]. Marusak C, et, al. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacol Res. 2016 Nov;113(Pt A):515-520.
















