Myristic acid-d2 is intended for use as an internal standard for the quantification of myristic acid by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.1,2
1.Bhatnagar, R.S., FÜtterer, K., Waksman, G., et al.The structure of myristoyl-CoA: Protein N-myristoyltransferaseBiochim. Biophys. Acta1441(2-3)162-172(1999) 2.Martin, D.D.O., Beauchamp, E., and Berthiaume, L.G.Post-translational myristoylation: Fat matters in cellular life and deathBiochimie93(1)18-31(2011)