IC50: 0.1 μM (RPTPβ/ζ), 0.7 μM (PTP-1B)[1]
MY33-3 is a potent and selective inhibitor of receptor protein tyrosine Reduced ethanol consumption when comparing day 2 with day 3.
Showed a reduced preference for the ethanol solution.
Not affected total fluid consumption.
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[3]. Mao S, et, al. Pleiotrophin Potentiates Sevoflurane Anesthesia-induced Learning Deficits in Mice. J Mol Neurosci. 2022 Jan;72(1):48-55.