ML 400 is a potent and selective LMPTP inhibitor with an IC50 value of 1680 nM. ML 400 inhibits adipogenesis.
ML 400 (10 µM; 2 days) prevents adipogenesis in 3T3-L1 Cells[1].
References:
[1]. Ardecky RJ, et al. Allosteric Small Molecule Inhibitors of LMPTP. 2014 Apr 15 [updated 2015 Jan 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.