GlpBio

Lyso-Monosialoganglioside GM2 (ammonium salt)

目录号: GC48345纯度: >98.00%同义词: Lysoganglioside GM2, Lyso-GM2, lyso-Monosialoganglioside GM2
A sphingolipid
Lyso-Monosialoganglioside GM2 (ammonium salt)
规格价格库存数量操作
500µg¥11,211.00现货
1
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产品描述 Description

Lyso-monosialoganglioside GM2 (Lyso-GM2) is a form of ganglioside GM2 that is lacking the fatty acyl group. Lyso-GM2 inhibits PKC in a cell-free assay (IC50 = 50 µM).1 Levels of lyso-GM2 are increased in the gray matter of postmortem brain samples from patients with Sandhoff disease or Tay-Sachs disease, as well as in a mouse model of Sandhoff disease.2,3 [Matreya, LLC. Catalog No. 1543]

1.Hannun, Y.A., and Bell, R.M.Lysosphingolipids inhibit protein kinase C: Implications for the sphingolipidosesScience235(4789)670-674(1987) 2.Kobayashi, T., Goto, I., Okada, S., et al.Accumulation of lysosphingolipids in tissues from patients with GM1 and GM2 gangliosidosesJ. Neurochem.59(4)1452-1458(1992) 3.Kodama, T., Togawa, T., Tsukimura, T., et al.Lyso-GM2 ganglioside: A possible biomarker of Tay-Sachs disease and Sandhoff diseasePLoS One6(12)e29074(2011)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

同义词
Lysoganglioside GM2, Lyso-GM2, lyso-Monosialoganglioside GM2
SMILES
N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O)O)CO)O[C@]4(C([O-])=O)C[C@H](O)[C@@H](NC(C)=O)[C@@]([C@@H]([C@H](O)CO)O)([H])O4)O)CO.[NH4+]
分子式
C49H86N3O25•NH4
分子量
1135.3 g/mol
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol