EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 Intraperitoneal injection; 30 min before killedInhibited β-droxylase of 3H-α-metldopamine.
Reduced the amount of 3H-α-Me-NA by 12%.
[1]. Fowler CJ, et al. Inhibition of inositol 1,4,5-trisphosphate 5-phosphatase by micromolar concentrations of disulfiram and its analogues. Biochem J. 1993 Feb 1;289 ( Pt 3)(Pt 3):853-9.
[2]. Carlsson A, et al. On the beta-droxylation of (+-)-alpha-metldopamine in vivo. Eur J Pharmacol. 1968 Dec;5(1):85-92.
















