Elaidyl alcohol is a monounsaturated fatty alcohol produced by the hydrogenation of elaidic acid .1 It is active against herpes simplex virus 2 (HSV-2) and bacteriophage ?6, but not Pseudoalteromonas phage PM2, virions in plaque assays (IC50s = 1.9, 0.4, and >75 µM, respectively).2 Elaidyl alcohol has been used in the formation of bimolecular films to study the effect of unsaturation on model lipid membranes.3
1.Cheah, K.Y., Tang, T.S., Mizukami, F., et al.Selective hydrogenation of oleic acid to 9-octadecen-1-ol: Catalyst preparation and optimum reaction conditionsJ. Am. Oil Chem. Soc.69(5)410-416(1992) 2.Sands, J., Auperin, D., and Snipes, W.Extreme sensitivity of enveloped viruses, including herpes simplex, to long-chain unsaturated monoglycerides and alcoholsAntimicrob. Agents Chemother.15(1)67-73(1979) 3.Legaly, G., Weiss, A., and Stuke, E.Effect of double-bonds on bimolecular films in membrane modelsBiochim. Biophys. Acta470(3)331-341(1977)