Creatinine-D3 is a deuterium-labeled creatinine compound. Creatinine-D3 serves as an internal standard for accurate quantitative analysis of creatinine via GC- or LC-mass spectrometry. Creatinine-D3 can be applied in research related to renal function assessment, muscle mass measurement, and aging metabolism studies[1-4].
References:
[1] Allen PJ. Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value? Neurosci Biobehav Rev. 2012 May;36(5):1442-62.
[2] Zhang Q, Qin Z, Wang Q, et al. Pharmacokinetic profiling of ZCL-278, a cdc42 inhibitor, and its effectiveness against chronic kidney disease. Biomed Pharmacother. 2024 Oct;179:117329.
[3] Hu C, Zhang JQ, Zhuang XY, et al. The hidden potential of solasonine: Targeting non-small cell lung cancer (NSCLC) metastasis through GATM and Smad2 pathways. Phytomedicine. 2025 Apr;139:156455.
[4] Xu C, Zhang M, Zhang S, et al. Simultaneous determination of choline, L-carnitine, betaine, trimethylamine, trimethylamine N-oxide, and creatinine in plasma, liver, and feces of hyperlipidemic rats by UHPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Aug 1;1243:124210.
Creatinine-D3是一种氘标记的肌酸酐化合物。Creatinine-D3可作为内标物通过GC-或LC-质谱法对肌酸酐进行精确定量分析。Creatinine-D3可用于肾功能评估、肌肉质量测量和衰老代谢研究的相关研究[1-4]。