cis-Vaccenic acid-d13 is intended for use as an internal standard for the quantification of cis-vaccenic acid by GC- or LC-MS. cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.1 It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).2
1.Shibahara, A., Yamamoto, K., Nakayama, T., et al.cis-Vaccenic acid in mango pulp lipidsLipids21(6)388-394(1986) 2.Aimola, I.A., Inuwa, H.M., Nok, A.J., et al.Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cellsEur. J. Pharmacol.7769-18(2016)