Bromacil is a phytotoxic herbicide that inhibits growth of watermelon, molokhia, and wheat plants (EC50s = 4.77, 0.08, and 3.08 mg/kg of soil, respectively).1 It inhibits growth of mustard, pea, sugar beet, linseed, barley, maize, ryegrass, and buckwheat plants by greater than 90% when used at a concentration of 1 kg/hectare.2 In vivo, bromacil induces formation of thyroid tumors in rats and liver tumors in mice.3
1.El-Nahhal, Y., and Hamdona, N.Phytotoxicity of Alachlor, Bromacil and Diuron as single or mixed herbicides applied to wheat, melon, and molokhiaSpringerplus4:367(2015) 2.Cossey, A.L., and Phillips, J.N.3-Alkoxyuracil derivatives. 1. Herbicidal activityJ. Agric. Food Chem.29(4)716-718(1981) 3.Hurley, P.M.Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodentsEnviron. Health Perspect.106(8)437-445(1998)