GlpBio

Acetyl Hexapeptide-3 (acetate)

目录号: GC46786纯度: >95.00%同义词: Ac-EEMQRR-NH2, Acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2, Acetyl Hexapeptide-8
A synthetic hexapeptide
Acetyl Hexapeptide-3 (acetate)
Cas No.: N/A
规格价格库存数量操作
1 mg¥1,525.00现货
1
5 mg¥5,344.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Acetyl hexapeptide-3 is a synthetic acetylated and amidated hexapeptide consisting of amino acid residues 12-17 of synaptosomal-associated protein 25 (SNAP-25).1 It inhibits formation of the SNARE complex in vitro in a concentration-dependent manner. It also inhibits calcium-induced norepinephrine release in permeabilized chromaffin cells (IC50 = 110 μM). Acetyl hexapeptide-3 (10% in an oil-and-water emulsion) inhibits decreases in type I collagen levels and skin thickness, as well as increases in type III collagen levels, in skin in a mouse model of subacute aging induced by D-galactose when administered topically.2

1.Blanes-Mira, C., Clemente, J., Jodas, G., et al.A synthetic hexapeptide (argireline) with antiwrinkle activityInt. J. Cosmet. Sci.24(5)303-310(2002) 2.Wang, Y., Wang, M., Xiao, X.S., et al.The anti-wrinkle efficacy of argirelineJ. Cosmet Laser Ther.15(4)237-241(2013)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
N/A
同义词
Ac-EEMQRR-NH2, Acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2, Acetyl Hexapeptide-8
SMILES
OC(CC[C@H](NC(C)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)CCSC)=O)CCC(O)=O)=O)=O.CC(O)=O
分子式
C34H60N14O12S.XC2H4O2
分子量
889 g/mol
溶解性
PBS (pH 7.2): 10 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol