9-Oxononanoic acid is an oxidized fatty acid formed via the autoxidation of linoleic acid .1,2 It increases phospholipase A2 (PLA2) activity and production of thromboxane B2 in isolated human plasma.1 9-Oxononanoic acid decreases hepatic de novo fatty acid synthesis and increases hepatic carnitine palmitoyltransferase activity, a marker of β-oxidation, in rats.2
1.Ren, R.F., Hashimoto, T., Mizuno, M., et al.A lipid peroxidation product 9-oxononanoic acid induces phospholipase A2 activity and thromboxane A2 production in human bloodJ. Clin. Biochem. Nutr.52(3)228-233(2013) 2.Minamoto, S., Kanazawa, K., Ashida, H., et al.Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liverBiochim. Biophys. Acta958(2)199-204(1988)