GlpBio

11-Beta-hydroxyandrostenedione

目录号: GC39223纯度: >98.50%同义词: 4-雄烯-11β-醇-3,17-二酮,4-Androsten-11β-ol-3,17-dione
11β-Hydroxyandrostenedione是一种内源性、天然存在的?类固醇和雄激素原，主要（如果不是完全）在肾上腺中产生。它与肾上腺产生的肾上腺素(11-ketoandrostenedione; 11-KA4)、11-ketotestosterone?(11-KT) 和11-ketodihydrotestosterone?(11-KDHT)密切相关。可用作指导肾上腺静脉取样中原发性醛固酮增多症亚型的生物标志物，其中从两个肾上腺采集血样以比较每个腺体产生的激素量。
11-Beta-hydroxyandrostenedione
Cas No.: 382-44-5
规格价格库存数量操作
5mg¥360.00现货
1
10mg¥576.00现货
1
25mg¥1,152.00现货
1
50mg¥1,843.00现货
1
10mM (in 1mL DMSO)¥396.00现货
1
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文献被引

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    31, 1291–1307 (2021)

产品描述 Description

4-Androsten-11β-ol-3,17-dione (11OHA4) is a steroid that has been found in isolated human female adrenal veins.1 It is non-androgenic, however, it is metabolized to the androgenic 5α-reduced C19 steroids 11-hydroxy-5α-androstanedione, 11-keto-5α-androstanedione, 11-hydroxydihydrotestosterone, and 11-ketodihydrotestosterone in LNCaP cells.

1.Storbeck, K.-H., Bloem, L.M., Africander, D., et al.11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?Mol. Cell. Endocrinol.377(1-2)135-146(2013)

产品文档 Product Documents

Purity:>98.50%

化学性质Chemical Properties

CAS 号
382-44-5
同义词
4-雄烯-11β-醇-3,17-二酮,4-Androsten-11β-ol-3,17-dione
SMILES
C[C@]12CCC(C=C1CC[C@@]([C@]2([H])[C@@H](O)C[C@@]34C)([H])[C@]3([H])CCC4=O)=O
分子式
C19H26O3
分子量
302.41 g/mol
溶解性
DMSO: 250 mg/mL (826.69 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol