Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins.
References:
[1]. Kesik M, Jedlina-Panasiuk L, Kozak-Cieszczyk M, Płucienniczak A, Wedrychowicz H. Enteral vaccination of rats against Fasciola hepatica using recombinant cysteine proteinase (cathepsin L1). Vaccine. 2007 May 4;25(18):3619-28.