Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis[1].
Wnt/β-catenin agonist 3 (compound 98; 24 h; HEK293 and SW480 cells) has 54% cell activity at 120 μM concentration compared with the positive control group LiCl (20mM)[1].
Wnt/β-catenin agonist 3 (30 and 60 μM; 24 h; HEK293 cells) is an activator for β-Catenin and deposits β-catenin[1].
Wnt/β-catenin agonist 3 (11 μM; 4 d) induces differentiation of ST2 cell line into osteoblasts and calcium deposition[1].
Western Blot Analysis[1]
| Cell Line: | HEK293 cells |
| Concentration: | 30 and 60 μM |
| Incubation Time: | 24 hours |
| Result: | Deposited β-catenin in a dose-dependent pattern within cells. |