GlpBio

USP7-IN-8

目录号: GC62377纯度: >98.50%
USP7-IN-8 (example 81) 是一种选择性的泛素特异性蛋白酶 7 (USP7) 抑制剂，在 Ub-Rho110 分析中的 IC50 为 1.4 μM。USP7-IN-8 对 USP47 和 USP5 没有活性。USP7-IN-8 具有抗癌作用。
USP7-IN-8
Cas No.: 2009273-60-1
规格价格库存数量操作
1mg¥463.00现货
1
5mg¥1,101.00现货
1
10mg¥1,767.00现货
1
25mg¥2,982.00现货
1
50mg¥4,264.00现货
1
10mM (in 1mL DMSO)¥842.00现货
1
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产品描述 Description

USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects[1].

USP7 or HAUSP (herpesvirus-associated USP) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates. USP7 is a eubiquitinase (DUB) that controls cell proliferation by altering the stability of Mdm2, p53, PTEN and FOXO4[1].

[1]. Robert Blake, et al. Usp7 inhibitor compounds and methods of use. US20160272588A1.

产品文档 Product Documents

Purity:>98.50%

化学性质Chemical Properties

CAS 号
2009273-60-1
分子式
C21H21N3O2
分子量
347.41 g/mol
溶解性
DMSO : 83.33 mg/mL (239.86 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol