USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 μM. USP15-IN-1 can be used for researching anticancer[1].
USP15-IN-1 (compound IM001) (0.001-5 μM; 48 h) exhibits highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells[1].
Cell Proliferation Assay[1]
| Cell Line: | Non-small cell lung carcinoma and leukemia cells |
| Concentration: | 0.001 μM, 0.005 μM, 0.01 μM, 0.05 μM, 0.1 μM, 0.5 μM, 1 and 5 μM |
| Incubation Time: | 48 h |
| Result: | Exhibited highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells with IC50s of 1.94 μM and 2.22 μM. |
[1]. Chen Yihua, et al. The tetrahydro-beta-carboline micromolecular organic compound and its derivative and medical usage of a kind of hydroxyl substitution. CN108727370A