GlpBio

USP1-IN-3

目录号: GC73156纯度: >99.00%
USP1-IN-3是一种选择性USPI抑制剂。
USP1-IN-3
Cas No.: 2821749-58-8
规格价格库存数量操作
1 mg¥2,745.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of ＜30 nM. USP1-IN-3 can be used for the research of cancer.

USP1-IN-3 has inhibitory against USPI-UAFI with an IC50 value of ＜30 nM[1].USP1-IN-3 has viability for a non-isogenic pair of BRCAI mutant and BRCAI WT cell lines with IC50 values of ＜100 nM and ＞ 10 μM, respectively[1].

References:
[1]. Scott Throner, et al. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer. Patent. WO2022174184A1.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
2821749-58-8
分子式
C27H24F3N7O
分子量
519.52 g/mol
溶解性
DMSO : 100 mg/mL (192.49 mM; Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol