UoS 12258

目录号: GC50428纯度: >98%
A positive allosteric modulator of AMPA receptors

UoS 12258
Cas No.: 875927-64-3
规格价格库存数量操作
5mg¥1,215.00现货
1
10mg¥1,980.00现货
1

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产品描述 Description

Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro). Also potentiates AMPA-mediated synaptic responses in vivo. Improves performance of rats in various learning and memory paradigms

Ward et al (2010) Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator. J.Med.Chem. 53 5801 PMID:20614889 |Ward et al (2017) Pharmacological characterization of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide: a novel, clinical AMPA receptor positive allosteric modulator. Br.J.Pharmacol. 174 370 PMID:28009436

产品文档 Product Documents

化学性质Chemical Properties

CAS 号
875927-64-3
SMILES
CC(S(=O)(N[C@H]1CC2=CC=C(C3=CN=C(C=C3)F)C=C2C1)=O)C
分子式
C17H19FN2O2S
分子量
334.41 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol