GlpBio

UCB-9260

目录号: GC62346纯度: >98.00%
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 ?nM. UCB-9260 also inhibits NF-κB with IC50 of 202?nM after TNF stimulation.
UCB-9260
Cas No.: 1515888-53-5
规格价格库存数量操作
1mg¥490.00现货
1
5mg¥1,190.00现货
1
10mg¥2,100.00现货
1
10mM (in 1mL DMSO)¥1,309.00现货
1
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文献被引

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产品描述 Description

UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 ?nM. UCB-9260 also inhibits NF-κB with IC50 of 202?nM after TNF stimulation.

[1] James O'Connell, et al. Nat Commun. 2019 Dec 19;10(1):5795.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
1515888-53-5
分子式
C26H25N5O
分子量
423.51 g/mol
溶解性
DMSO : 125 mg/mL (295.15 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol