TIMP2 Human HEK

目录号: GP22303纯度: >98%
Tissue Inhibitor of Metalloprotease 2 Human Recombinant, HEK

TIMP2 Human HEK
规格价格库存数量操作
2μg¥840.00现货
1
10μg¥2,030.00现货
1
1mg¥65,520.00现货
1

文献被引

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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

TIMP2 Human Recombinant produced in HEK-293 cells is a secreted protein with the sequence of Human TIMP-2 (amino acids Cys27-Pro220) and is fused to a polyhistidine tag at the C-terminus.

产品文档 Product Documents

Product Data

Purity
Greater than 95.0% as determined by SDS-PAGE.
Source
HEK293 Cells.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Shipping Condition
Shipped at Room temp.
Synonyms
TIMP metallopeptidase inhibitor 2; CSC-21K; tissue inhibitor of metalloproteinase 2; TIMP-2; metalloproteinase inhibitor 2.
Solubility
It is recommended to reconstitute the lyophilized TIMP2 in sterile assay buffer (50mM Tris, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35, PH 7.5) not less than 100µg/ml.
Stability
Lyophilized TIMP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution TIMP2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Biological Activity
The IC50 of 3 nM is measured by its ability to inhibit recombinant human MMP-2 cleavage of the colorimetric peptide substrate, Mca-PLGL-DpaAR-NH2.
Formulation
The TIMP2 protein was lyophilized after extensive dialysis against PBS.