GlpBio

Streptogramin B

目录号: GC48111纯度: >98.00%同义词: Mikamycin B; Mikamycin IA
A macrolide antibiotic
Streptogramin B
Cas No.: 3131-03-1
规格价格库存数量操作
1 mg¥1,063.00现货
1
5 mg¥3,188.00现货
1
10 mg¥5,313.00现货
1
25 mg¥11,950.00现货
1
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文献被引

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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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产品描述 Description

Streptogramin B is a macrolide antibiotic.1 It inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species (MIC90s = 2, 0.5, and 8 μg/ml, respectively).2 Streptogramin B inhibits protein synthesis by interacting with the 50S ribosome.1 Resistance to streptogramin B is conferred by erythromycin ribosome methylation (erm) genes, which code for methylases that methylate the 50S ribosome, interfering with streptogramin B binding.

1.Roberts, M.C., Sutcliffe, J., Courvalin, P., et al.Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinantsAntimicrob. Agents Chemother.43(12)2823-2830(1999) 2.Laforest, H., Fourgeaud, M., Richet, H., et al.Comparative in vitro activities of pristinamycin, its components, and other antimicrobial agents against anaerobic bacteriaAntimicrob. Agents Chemother.32(7)1094-1096(1988)

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
3131-03-1
同义词
Mikamycin B; Mikamycin IA
SMILES
O=C1C[C@](C(N[C@@H](C2=CC=CC=C2)C(O[C@H](C)[C@H](NC(C3=C(O)C=CC=N3)=O)C4=O)=O)=O)([H])N(C([C@@](CC5=CC=C(N(C)C)C=C5)([H])N(C)C([C@]6([H])CCCN6C([C@H](N4)CC)=O)=O)=O)CC1
分子式
C45H54N8O10
分子量
867 g/mol
溶解性
Chloroform: 30 mg/ml,DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol