GlpBio

SP-420

目录号: GC30340纯度: >99.50%同义词: (4S)-4,5-二氢-2-[2-羟基-4-[2-(2-甲氧基乙氧基)乙氧基]苯基]-4-甲基-4-噻唑羧酸
An iron chelator
SP-420
Cas No.: 911714-45-9
规格价格库存数量操作
1mg¥288.00现货
1
5mg¥608.00现货
1
10mg¥972.00现货
1
25mg¥2,025.00现货
1
50mg¥3,240.00现货
1
100mg¥5,184.00现货
1
10mM (in 1mL DMSO)¥668.00现货
1
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产品描述 Description

SP 420 is an iron chelator and a derivative of desferrothiocin.1 It induces iron excretion in rat bile and urine with an iron-clearing efficiency (ICE) value of 26.7% when administered at a dose of 300 μmol/kg and decreases iron levels in rat liver and heart at 384 μmol/kg per day. SP 420 (75 μmol/kg) also induces iron excretion in iron-overloaded C. apella monkeys (ICE = 26.3%).

1.Bergeron, R.J., Bharti, N., Wiegand, J., et al.The impact of polyether chain length on the iron clearing efficiency and physiochemical properties of desferrithiocin analoguesJ. Med. Chem.53(7)2843-2853(2010)

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
911714-45-9
同义词
(4S)-4,5-二氢-2-[2-羟基-4-[2-(2-甲氧基乙氧基)乙氧基]苯基]-4-甲基-4-噻唑羧酸
SMILES
O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O
分子式
C16H21NO6S
分子量
355.41 g/mol
溶解性
DMSO : ≥ 38 mg/mL (106.92 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol