关于 "Reverse Transcriptase" 的结果28+ 个结果
- Reverse transcriptase-IN-1CAS: 2380001-43-2
Reverse transcriptase-IN-1 (Compound 12z),二芳基苯并嘧啶 (DABP) 类似物, 是一种有效的,具有口服活性的 HIV-1 非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性,对 HIV-1 IIIB,E138K 和 K103N 突变体的 EC50 值分别为 3.4 nM,4.3 nM 和 3.6 nM,而且对 HIV-1 逆转录酶的 IC50 值为 13.7 nM。
- M-MLV Reverse transcriptaseCAS: 9068-38-6
M-MLV Reverse transcriptase (M-MLV RT) 是一种逆转录酶,最早来源于莫洛尼鼠白血病病毒 ( Moloneymurineleukemiavirus , MoMLV)。
- Tenofovir diphosphate (sodium salt)
An HIV reverse transcriptase and HBV polymerase inhibitor
- 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt)
An inhibitor of reverse transcriptases and DNA polymerases
- TirucallolCAS: 514-46-5
A triterpenoid with reverse transcriptase inhibitory and anti-inflammatory activities
- ElsulfavirineCAS: 868046-19-9
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.
- Cyanine 5-6-Propargylamino-2’-deoxyuridine-5’-Triphosphate
Cyanine 5-6-Propargylamino-2’-deoxyuridine-5’-Triphosphate can replace dTTP in many enzymatic reactions, as it is a substrate for many polymerases and reverse transcriptases.
- Rilpivirine HydrochlorideCAS: 700361-47-3
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
- Tenofovir alafenamide fumarateCAS: 379270-38-9
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
- Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human)CAS: 139227-42-2
Asn-Ala-ICAM 1 (1-21) inhibits virus replication in HIV-1 infected HTLV-1 transformed cells (MT-2 cells). The peptide induces up to 70% inhibition of reverse transcriptase activity, up to 60% reduction of soluble virus antigen production, and inhibition of syncytium formation.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC63523 | Reverse transcriptase-IN-1 | 2380001-43-2 | HIV | ||
Reverse transcriptase-IN-1 (Compound 12z),二芳基苯并嘧啶 (DABP) 类似物, 是一种有效的,具有口服活性的 HIV-1 非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性,对 HIV-1 IIIB,E138K 和 K103N 突变体的 EC50 值分别为 3.4 nM,4.3 nM 和 3.6 nM,而且对 HIV-1 逆转录酶的 IC50 值为 13.7 nM。 | |||||
| GF07452 | M-MLV Reverse transcriptase | 9068-38-6 | - | ||
M-MLV Reverse transcriptase (M-MLV RT) 是一种逆转录酶,最早来源于莫洛尼鼠白血病病毒 (Moloneymurineleukemiavirus, MoMLV)。 | |||||
| GC32306 | Islatravir (MK-8591) | 865363-93-5 | Reverse Transcriptase | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC13653 | Emtricitabine | 143491-57-0 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC14720 | Zalcitabine | 7481-89-2 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC49776 | Apricitabine | 160707-69-7 | HIV | ||
A nucleoside reverse transcriptase inhibitor | |||||
| GC32390 | MIV-150 (PC 815) | 231957-54-3 | HIV | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC19126 | Doravirine | 1338225-97-0 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC14452 | Dapivirine (TMC120) | 244767-67-7 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC15452 | Delavirdine mesylate | 147221-93-0 | HIV | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC35835 | Delavirdine | 136817-59-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC37690 | Stavudine sodium | 134624-73-0 | Reverse Transcriptase | ||
An inhibitor of HIV reverse transcriptase | |||||
| GC60357 | Tenofovir diphosphate | 166403-66-3 | Reverse Transcriptase | ||
An HIV reverse transcriptase and HBV polymerase inhibitor | |||||
| GC45012 | Tenofovir diphosphate (sodium salt) | - | Drug Metabolite | ||
An HIV reverse transcriptase and HBV polymerase inhibitor | |||||
| GC52501 | 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt) | - | HIV | ||
An inhibitor of reverse transcriptases and DNA polymerases | |||||
| GC15330 | Didanosine | 69655-05-6 | HIV | ||
An antiviral nucleoside analog and inhibitor of reverse transcriptase | |||||
| GC63228 | Tirucallol | 514-46-5 | Others | ||
A triterpenoid with reverse transcriptase inhibitory and anti-inflammatory activities | |||||
| GC11059 | Rilpivirine | 500287-72-9 | Reverse Transcriptase | ||
A non-nucleoside reverse transcriptase inhibitor | |||||
| GC12830 | Stavudine (d4T) | 3056-17-5 | Other Apoptosis | ||
An inhibitor of HIV reverse transcriptase | |||||
| GC62295 | Elsulfavirine | 868046-19-9 | HIV | ||
Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection. | |||||
| GN20141 | Cyanine 5-6-Propargylamino-2’-deoxyuridine-5’-Triphosphate | - | - | ||
Cyanine 5-6-Propargylamino-2’-deoxyuridine-5’-Triphosphate can replace dTTP in many enzymatic reactions, as it is a substrate for many polymerases and reverse transcriptases. | |||||
| GC25867 | Rilpivirine Hydrochloride | 700361-47-3 | Reverse Transcriptase | ||
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. | |||||
| GC37758 | Tenofovir alafenamide fumarate | 379270-38-9 | Reverse Transcriptase | ||
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. | |||||
| GA20781 | Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human) | 139227-42-2 | - | ||
Asn-Ala-ICAM 1 (1-21) inhibits virus replication in HIV-1 infected HTLV-1 transformed cells (MT-2 cells). The peptide induces up to 70% inhibition of reverse transcriptase activity, up to 60% reduction of soluble virus antigen production, and inhibition of syncytium formation. | |||||
