关于 "Insulin Receptor" 的结果18+ 个结果
- Insulin receptor (1142-1153), pTyr1150CAS: 134177-41-6
Insulin receptor (1142-1153), pTyr1150是一种生物活性肽。
- [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153CAS: 141171-54-2
[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) 与胰岛素结合,可作为胰岛素受体酪氨酸激酶底物。
- Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human)CAS: 172615-51-9
Substrate for the insulin-like growth factor 1 receptor (IGF-1R) tyrosine kinase domain (Km 26 ± 3.9 µM; kcat/Km 2.6 . 10³ M?¹min?¹). The sequence is based on the phosphorylation site Tyr??? of the 185 kDa insulin receptor substrate-1 protein (IRS-1).
- MID-1CAS: 312608-54-1
MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction, which can disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
- Fmoc-Tyr(malonyl-di-OtBu)-OHCAS: 168135-77-1
The phosphotyrosine-mimicking amino acid Fmoc-Tyr(malonyl-di-OtBu)-OH can be used as a building block for the synthesis of cell-permeable protein tyrosine phosphatase (PTP) inhibitors. The effect of a malonyl-tyrosine containing peptide on PTP 1B catalyzed insulin receptor dephosphorylation has been examined and it was shown that this peptide inhibited PTP 1B 20 times more potently than the corresponding phosphotyrosine containing peptide.
- Insulin degludecCAS: 844439-96-9
Insulin degludec 是一种超长效形式的胰岛素,用于治疗 1 型和 2 型糖尿病引起的高血糖。Insulin degludec 结合胰岛素受体的 IC50 值为 19.59 nM/L。Insulin degludec 可用于 1 型和 2 型糖尿病的研究。
- Insulin aspartCAS: 116094-23-6
Insulin aspart (B28Asp) 是一种快速作用的人胰岛素类似物。经皮下注射后,Insulin aspart 比普通人胰岛素吸收更快。门冬胰岛素可用于糖尿病的研究。
- Insulin DetemirCAS: 169148-63-4
Insulin Detemir 是一种人工胰岛素,具有控制血糖水平的作用。Insulin Detemir 通过激活 Akt 和细胞外信号调节激酶 (ERK) 依赖的-cat 和 CREB 信号通路,促进 Gcg 表达,从而刺激 GLP-1 的分泌。地特胰岛素可用于 2 型糖尿病的研究。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC72276 | Insulin receptor (1142-1153), pTyr1150 | 134177-41-6 | Enzyme Substrates | ||
Insulin receptor (1142-1153), pTyr1150是一种生物活性肽。 | |||||
| GC35023 | [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153 | 141171-54-2 | Peptides | ||
[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) 与胰岛素结合,可作为胰岛素受体酪氨酸激酶底物。 | |||||
| GP20677 | INSR Human | - | Insulin | ||
Insulin Receptor Human Recombinant | |||||
| GC13988 | HNMPA | 132541-52-7 | Insulin Receptor | ||
An insulin receptor tyrosine kinase inhibitor | |||||
| GC39189 | S961 TFA | - | Peptides | ||
S961 is a biosynthetic insulin receptor antagonist that inhibits cellular proliferation and colony formation in breast tumour cells. | |||||
| GC25881 | S961 | 1083433-49-1 | IGF1R | ||
S961 is a biosynthetic insulin receptor antagonist that inhibits cellular proliferation and colony formation in breast tumour cells. | |||||
| GA23160 | Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human) | 172615-51-9 | - | ||
Substrate for the insulin-like growth factor 1 receptor (IGF-1R) tyrosine kinase domain (Km 26 ± 3.9 µM; kcat/Km 2.6 . 10³ M?¹min?¹). The sequence is based on the phosphorylation site Tyr??? of the 185 kDa insulin receptor substrate-1 protein (IRS-1). | |||||
| GC61516 | MID-1 | 312608-54-1 | Insulin Receptor | ||
MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction, which can disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake. | |||||
| GA21826 | Fmoc-Tyr(malonyl-di-OtBu)-OH | 168135-77-1 | - | ||
The phosphotyrosine-mimicking amino acid Fmoc-Tyr(malonyl-di-OtBu)-OH can be used as a building block for the synthesis of cell-permeable protein tyrosine phosphatase (PTP) inhibitors. The effect of a malonyl-tyrosine containing peptide on PTP 1B catalyzed insulin receptor dephosphorylation has been examined and it was shown that this peptide inhibited PTP 1B 20 times more potently than the corresponding phosphotyrosine containing peptide. | |||||
| GP20673 | Insulin Human | - | Peptides | ||
人胰岛素(Insulin Human)是重组人胰岛素 | |||||
| GC31303 | Insulin(cattle) (Insulin from bovine pancreas) | 11070-73-8 | Peptides | ||
胰岛素是一种由21个和30个氨基酸组成的激素蛋白质。 | |||||
| GP20676 | Insulin Porcine | 12584-58-6 | Insulin | ||
猪胰岛素 | |||||
| GC67998 | Insulin degludec | 844439-96-9 | Insulin Receptor | ||
Insulin degludec 是一种超长效形式的胰岛素,用于治疗 1 型和 2 型糖尿病引起的高血糖。Insulin degludec 结合胰岛素受体的 IC50 值为 19.59 nM/L。Insulin degludec 可用于 1 型和 2 型糖尿病的研究。 | |||||
| GC20187 | Insulin aspart | 116094-23-6 | - | ||
Insulin aspart (B28Asp) 是一种快速作用的人胰岛素类似物。经皮下注射后,Insulin aspart 比普通人胰岛素吸收更快。门冬胰岛素可用于糖尿病的研究。 | |||||
| GP20674 | Insulin Human, Yeast | - | Insulin | ||
Insulin Human Recombinant, Yeast | |||||
| GP20675 | Insulin Human, His | - | Insulin | ||
Insulin Human Recombinant, His Tag | |||||
| GC69282 | Insulin Detemir | 169148-63-4 | Akt | ||
Insulin Detemir 是一种人工胰岛素,具有控制血糖水平的作用。Insulin Detemir 通过激活 Akt 和细胞外信号调节激酶 (ERK) 依赖的-cat 和 CREB 信号通路,促进 Gcg 表达,从而刺激 GLP-1 的分泌。地特胰岛素可用于 2 型糖尿病的研究。 | |||||
| GC69283 | Insulin glargine | 160337-95-1 | Insulin Receptor | ||
Insulin glargine 是一种长效胰岛素类似物。Insulin glargine 可用于研究糖尿病。 | |||||
