关于 "Glucose Transporters" 的结果6 个结果
筛选:SGLT×
- Tofogliflozin (CSG452)CAS: 903565-83-3
Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
SGLT - Ertugliflozin L-pyroglutamic acidCAS: 1210344-83-4
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
SGLT - DapagliflozinCAS: 461432-26-8
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。
SGLT
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC31461 | Tofogliflozin (CSG452) | 903565-83-3 | SGLT | ||
Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively. | |||||
| GC17976 | Phloretin | 60-82-2 | SGLT | ||
A natural inhibitor of various transporters | |||||
| GN10029 | Phloridzin | 60-81-1 | Na+/K+ ATPase | ||
An inhibitor of sodium-glucose cotransporters | |||||
| GC36004 | Ertugliflozin L-pyroglutamic acid | 1210344-83-4 | SGLT | ||
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus. | |||||
| GC15530 | Dapagliflozin | 461432-26-8 | SGLT | ||
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。 | |||||
| GC16697 | fluoro-Dapagliflozin | 1181681-43-5 | SGLT | ||
A potent inhibitor of hSGLT2 | |||||