关于 "Glucose Transporters" 的结果33 个结果
- YUM70CAS: 423145-35-1
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism.
- Glucosamine (D-Glucosamine)CAS: 3416-24-8
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
- L-Carnitine hydrochlorideCAS: 6645-46-1
L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation.
- Elamipretide (MTP-131)CAS: 736992-21-5
Elamipretide (MTP-131) 作为一种水溶性四肽，可以增强细胞 ATP 合成，从而改善电子传输并减少 ROS 的形成。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GN10668 | Coenzyme Q10 | 303-98-0 | Reactive Oxygen Species | ||
A cofactor in the electron transport chain | |||||
| GC62388 | YUM70 | 423145-35-1 | Apoptosis | ||
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism. | |||||
| GC30263 | Glucosamine (D-Glucosamine) | 3416-24-8 | Autophagy | ||
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites. | |||||
| GC38920 | L-Carnitine hydrochloride | 6645-46-1 | Endogenous Metabolite | ||
L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. | |||||
| GC11989 | Nortriptyline (hydrochloride) | 894-71-3 | Other Apoptosis | ||
A tricyclic antidepressant | |||||
| GC30795 | D-Galactose (D-(+)-Galactose) | 59-23-4 | Endogenous Metabolite | ||
A natural aldohexose | |||||
| GC16443 | 4-Aminohippuric Acid | 61-78-9 | Endogenous Metabolite | ||
A substrate for OAT1, NPT1, and MDR2 | |||||
| GC16775 | Rotenone | 83-79-4 | Other Apoptosis | ||
Rotenone是一种线粒体电子传递链复合物 I 抑制剂，可通过增强线粒体活性氧的产生来诱导细胞凋亡。 | |||||
| GC30014 | Elamipretide (MTP-131) | 736992-21-5 | Mitochondrial Metabolism | ||
Elamipretide (MTP-131) 作为一种水溶性四肽，可以增强细胞 ATP 合成，从而改善电子传输并减少 ROS 的形成。 | |||||