关于 "Nucleoside Antimetabolite/Analogue" 的结果21+ 个结果

PhentolamineAnalogue1是phentolamine的类似物。Phentolamine是一种非选择性的alpha-adrenergic拮抗剂。

Rezivertinib analogue 1 是一种甲磺酸奥希替尼的工艺杂质, 可用于非小细胞肺癌的研究。

(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxy acid 是一种受约束的 Phe 类似物，可以折叠成β-弯曲和螺旋结构，并在肽中采用优选的侧链排列。

A purine nucleoside

A neurotoxic pyridoxine antimetabolite

A norepinephrine analogue with anticancer activity

GET-73(Gamma hydroxybutyric acid analogue,GET 73,GHB analogue), a γ-hydroxybutyrate (GHB) analog, shows a neuroprotective role against ethanol-induced neurotoxicity in primary cultures of rat hippocampal neurons.

A purine nucleoside

A nucleoside analog

A nucleoside analog

An antiviral nucleoside analog

An imidazole nucleoside with immunosuppressive properties

An adenine nucleoside antibiotic with herbicidal activity

An active nucleoside metabolite of BMS-986094

S-Gboxin, a functional analogue of Gboxin, is an oxidative phosphorylation (OXPHOS) inhibitor which inhibits growth of mouse and human glioblastoma (GBM) with IC50 of 470 nM.

1,1,3-Tribromoacetone 是甲氨蝶呤 的杂质。Methotrexate (Amethopterin) 是一种抗代谢 (antimetabolite) 和抗叶酸剂 (antifolate)，可抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸并抑制 DNA 合成。

SIBA (5′-Isobutylthio-5′-deoxyadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 5'-Isobutylthioadenosine) is a synthetic analogue of S-adenosylhomocysteine and is a powerful antipro-liferative drug. SIBA is not only an inhibitor of transmethylation but also interferes with polyamine biosynthesis, probably by blocking aminopropyltransferase.

2-Deoxy-D-glucose (2DG)，是一种葡萄糖类似物，作为竞争性糖酵解抑制剂。

L-Ribulose 是 L-ribose 的异构体，是合成其他稀有糖和 L-nucleoside 类似物的重要前体。

Soluflazine 是一种具有抗惊厥作用的核苷转运 (nucleoside transport) 抑制剂。Soluflazine 可用作抗癫痫药。

DMT-dI (5'-O-DMT-dI) 是一种脱氧尿苷，可用于可转换核苷衍生物 (convertible nucleoside derivatives) 的制备。