SIBA

目录号: GC33442纯度: >99.50%同义词: 5ˊ-异丁硫基-5ˊ-脱氧腺苷,5'-Isobutylthioadenosine; 5'-Deoxy-5'-isobutylthioadenosine
SIBA (5′-Isobutylthio-5′-deoxyadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 5'-Isobutylthioadenosine) is a synthetic analogue of S-adenosylhomocysteine and is a powerful antipro-liferative drug. SIBA is not only an inhibitor of transmethylation but also interferes with polyamine biosynthesis, probably by blocking aminopropyltransferase.

SIBA
Cas No.: 35899-54-8
规格价格库存数量操作
1mg¥227.00现货
1
5mg¥588.00现货
1
10mg¥851.00现货
1
25mg¥1,654.00现货
1
50mg¥2,424.00现货
1
100mg¥3,457.00现货
1
10mM (in 1mL DMSO)¥439.00现货
1

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产品描述 Description

SIBA (5′-Isobutylthio-5′-deoxyadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 5'-Isobutylthioadenosine) is a synthetic analogue of S-adenosylhomocysteine and is a powerful antipro-liferative drug. SIBA is not only an inhibitor of transmethylation but also interferes with polyamine biosynthesis, probably by blocking aminopropyltransferase.

[1] M Carteni-Farina, et al. FEBS Lett. 1979 Aug 15;104(2):266-70. [2] F Lawrence,, et al. Biochem J. 1982 Jun 15;204(3):853-9.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
35899-54-8
同义词
5ˊ-异丁硫基-5ˊ-脱氧腺苷,5'-Isobutylthioadenosine; 5'-Deoxy-5'-isobutylthioadenosine
SMILES
O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3CSCC(C)C
分子式
C14H21N5O3S
分子量
339.41 g/mol
溶解性
DMSO : ≥ 100 mg/mL (294.63 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol