关于 "Nuclear Receptors" 的结果23+ 个结果
- TLX agonist 1CAS: 958323-31-4
TLX agonist 1 (CCRP2, SUN23314) is a modulator of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 1.0 μM and Kd of 650 nM. TLX agonist 1 (CCRP2, SUN23314) binds to recombinant TLX protein and enhances TLX transcriptional repressive activity.
Others - NOT Receptor Modulator 1CAS: 1015231-98-7
NOTReceptorModulator1是一种核受体NOT调节剂，详细信息请参考专利文献WO2008034974A1中Table1中的化合物Example39。
Others - Estrogen receptor modulator 1CAS: 63676-22-2
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM) with pIC50 of 0.46. Estrogen receptor modulator 1 exhibits potential anti-tumor activity.
- GPR34 receptor antagonist 2CAS: 907952-06-1
GPR34receptorantagonist2(CompoundD2)是GPR34受体拮抗剂，可用于免疫疾病，炎性疾病的研究。
Others - GPR52 receptor modulator 1CAS: 2642079-89-6
GPR52 receptor modulator 1(程序1)是一种GPR52受体调节剂，具有研究神经精神疾病的潜力。
Others - Succinate/succinate receptor antagonist 1CAS: 2361972-29-2
Succinate/succinate receptor antagonist 1 (compound 7a) 是一种琥珀酸受体拮抗剂。Succinate/succinate receptor antagonist 1 阻断牙龈组织中的琥珀酸信号。Succinate/succinate receptor antagonist 1 抑制琥珀酸受体 1 (SucnRl Antagonist 1) 的激活，IC50 值为 20 μμ。Succinate/succinate receptor antagonist 1 可用于牙周病的研究。
Others - NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)
A cell-permeable form of NFAT inhibitor
- NF-κB Inhibitor (trifluoroacetate salt)
A cell-permeable peptide that blocks nuclear import of NF-κB
- Apararenone (MT-3995)CAS: 945966-46-1
Apararenone (MT-3995) is a selective, long-acting nonsteroidal mineralocorticoid receptors (MR) antagonist.
- Nomegestrol acetateCAS: 58652-20-3
Nomegestrol Acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors.
- Nylidrin hydrochlorideCAS: 849-55-8
An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors
Others
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC10715 | GSK 4112 | 1216744-19-2 | Autophagy | ||
An agonist of the heme-dependent nuclear receptor REV-ERBα | |||||
| GC39261 | TLX agonist 1 | 958323-31-4 | Others | ||
TLX agonist 1 (CCRP2, SUN23314) is a modulator of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 1.0 μM and Kd of 650 nM. TLX agonist 1 (CCRP2, SUN23314) binds to recombinant TLX protein and enhances TLX transcriptional repressive activity. | |||||
| GC16363 | TGR5 Receptor Agonist | 1197300-24-5 | GPCR19 | ||
A TGR5 agonist | |||||
| GC31192 | NOT Receptor Modulator 1 | 1015231-98-7 | Others | ||
NOTReceptorModulator1是一种核受体NOT调节剂，详细信息请参考专利文献WO2008034974A1中Table1中的化合物Example39。 | |||||
| GC60816 | Estrogen receptor modulator 1 | 63676-22-2 | Estrogen Receptor/ERR | ||
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM) with pIC50 of 0.46. Estrogen receptor modulator 1 exhibits potential anti-tumor activity. | |||||
| GC61596 | GPR34 receptor antagonist 2 | 907952-06-1 | Others | ||
GPR34receptorantagonist2(CompoundD2)是GPR34受体拮抗剂，可用于免疫疾病，炎性疾病的研究。 | |||||
| GC71309 | GPR52 receptor modulator 1 | 2642079-89-6 | Others | ||
GPR52 receptor modulator 1(程序1)是一种GPR52受体调节剂，具有研究神经精神疾病的潜力。 | |||||
| GC71325 | P2X7 receptor antagonist-4 | - | Others | ||
P2X7 receptor antagonist-4（化合物14a）是P2X7R拮抗剂。 | |||||
| GC71335 | GPR34 receptor antagonist 3 | - | Others | ||
GPR34 receptor antagonist 3（化合物5e）是一类GRP34拮抗剂，IC50为0.680μM。 | |||||
| GC69966 | Succinate/succinate receptor antagonist 1 | 2361972-29-2 | Others | ||
Succinate/succinate receptor antagonist 1 (compound 7a) 是一种琥珀酸受体拮抗剂。Succinate/succinate receptor antagonist 1 阻断牙龈组织中的琥珀酸信号。Succinate/succinate receptor antagonist 1 抑制琥珀酸受体 1 (SucnRl Antagonist 1) 的激活，IC50 值为 20 μμ。Succinate/succinate receptor antagonist 1 可用于牙周病的研究。 | |||||
| GC52384 | NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) | - | Bone Growth & Remodeling | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC45073 | TRAP-6 Peptide (trifluoroacetate salt) | - | Coagulation & Hemostasis | ||
A PAR1 agonist | |||||
| GC52436 | TRAP-6 amide (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide PAR1 agonist | |||||
| GC90543 | EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt) | - | MDR multidrug resistance | ||
一种PKC抑制剂 | |||||
| GC48985 | NF-κB Inhibitor (trifluoroacetate salt) | - | Innate Immunity | ||
A cell-permeable peptide that blocks nuclear import of NF-κB | |||||
| GC11580 | BU 239 hydrochloride | 1217041-98-9 | Imidazoline Receptors | ||
Imidazoline receptors-selective antagonist | |||||
| GC45198 | α-CGRP (8-37) (human) (trifluoroacetate salt) | - | Others | ||
An antagonist of CGRP receptors | |||||
| GC16311 | Chlormethiazole hydrochloride | 6001-74-7 | Others | ||
A potentiator of GABAA receptors | |||||
| GC31448 | Apararenone (MT-3995) | 945966-46-1 | Mineralocorticoid Receptor | ||
Apararenone (MT-3995) is a selective, long-acting nonsteroidal mineralocorticoid receptors (MR) antagonist. | |||||
| GC36755 | Nomegestrol acetate | 58652-20-3 | Progesterone Receptor | ||
Nomegestrol Acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors. | |||||
| GC39414 | Nylidrin hydrochloride | 849-55-8 | Others | ||
An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors | |||||
| GC33117 | RCM-1 | 339163-65-4 | Others | ||
RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice. RCM-1 decreases carcinogenesis and nuclear β-catenin. | |||||
| GC48202 | Treprostinil (diethanolamine salt) | 830354-48-8 | Transcription Factors | ||
An agonist of IP2, DP2, and EP2 receptors | |||||