关于 "Aldehyde Dehydrogenase (ALDH)" 的结果16+ 个结果

Sorbitol dehydrogenase-IN-1是一种强效的口服活性山梨糖醇脱氮酶抑制剂，对大鼠和人类的IC50分别为4、5 nM。

An inhibitor of 17β-HSD3

Phenylglyoxal (1-Phenylethanedione) is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.

8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde.

A 3β-hydroxysteroid dehydrogenase inhibitor

An alcohol dehydrogenase inhibitor

Trans-2-hexenal (Leaf aldehyde) is an α,β-unsaturated carbonyl compound protecting plants against harmful substances.

KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses.

BODIPY-aminoacetaldehyde diethyl acetal（BAAA-DA）是BODIPY-氨基乙醛（BAAA）的稳定前体，BAAA是醛脱氢酶（ALDH）的细胞渗透性荧光底物，Ex/Em为488/512nm。

DCA 是癌细胞中的代谢调节剂'；具有抗癌活性的线粒体。 DCA 抑制 PDHK，导致肿瘤微环境中的乳酸减少。 DCA 增加活性氧 (ROS) 生成并促进癌细胞凋亡。 DCA 也可作为 NKCC 抑制剂。

An inhibitor of PDE2 and PDE3

A DYPD inhibitor

特立氟胺是来氟米特的活性代谢物，来氟米特是一种获准治疗类风湿性关节炎的药物。

BMS 566419 是一种基于吖啶酮的肌苷 5'-单磷酸脱氢酶 (IMPDH) 抑制剂。

A PHGDH inhibitor

PF 915275 是一种有效的、选择性的、具有口服活性的人 11β-羟基类固醇脱氢酶 1 型 (11βHSD1) 抑制剂，Ki 为 2.3 nM，EC50 为 15 nM（在 HEK293 细胞中）。