关于 "Cell Cycle/Checkpoint" 的结果17+ 个结果

A cellular senescence detection reagent

A glomerular epithelial cell toxin

Oleanonic Acid (3-Ketooleanolic Acid, 3-Oxooleanolic acid), extracted from Pistacia terebinthus galls, is a cell cycle inhibitor and used as antitumor agents.

Hesperadin是一种竞争性ATP结合抑制剂，对Aurora B激酶的IC 50 为250nM。

Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.

Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).

Deferasirox是一种具口服活性的铁螯合剂，用于治疗铁过载疾病。

A tumor cell-differentiating agent

Fasudil (HA-1077) HCl（法舒地尔；HA-1077；AT877）是一种非特异性RhoA/ROCK抑制剂，对ROCK1的K i 为0.33μM，IC 50 为0.158μM，对ROCK2和PKA、PKC、PKG的IC 50 分别为4.58μM、12.30μM、1.650μM。

An inhibitor of cyclin-dependent kinases

阿非迪霉素是真核DNA复制的可逆抑制剂，可阻断前S期的细胞周期。

DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease, which is a critical drug target for small molecule COVID-19, given its likely druggability and essentiality in the viral maturation and replication cycle.

A cell-permeable PKC inhibitor

A selective cancer stem cell inhibitor

A cell permeable inhibitor of PRMTs

A cell-permeable inhibitor of JMJD2 demethylases