关于 "Cell Cycle/Checkpoint" 的结果40+ 个结果
筛选:Cell Cycle/Checkpoint×
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC49723 | SenTraGor™ Cell Senescence Reagent | 2171036-89-6 | Cancer Biology | ||
A cellular senescence detection reagent | |||||
| GC10512 | Y-27632 dihydrochloride | 129830-38-2 | Other Apoptosis | ||
Y-27632 dihydrochloride 作为一种选择性 Rho 激酶抑制剂，是一种新型支气管扩张剂。 | |||||
| GC16684 | Docetaxel | 114977-28-5 | Other Apoptosis | ||
Docetaxel是紫杉烷类抗有丝分裂化疗药物,IC50为0.2 µM。 | |||||
| GC16822 | LY2835219 | 1231930-82-7 | CDK | ||
LY2835219是 CDK4 和 CDK6 的强效选择性抑制剂，在非细胞实验中的 IC50 分别为 2nM 和 10nM。 | |||||
| GC17648 | Dinaciclib(SCH727965) | 779353-01-4 | Other Apoptosis | ||
A CDK inhibitor | |||||
| GC10842 | LEE011 | 1211441-98-3 | CDK | ||
LEE011是一种具有口服活性的特异性细胞周期蛋白依赖性激酶CDK4/6抑制剂。LEE011以纳摩尔浓度靶向cyclin D1/CDK4和cyclin D3/CDK6。 | |||||
| GC17196 | Hesperadin | 422513-13-1 | Parasite | ||
Hesperadin是一种竞争性ATP结合抑制剂，对Aurora B激酶的IC50为250nM。 | |||||
| GC10546 | AZD7762 | 860352-01-8 | Checkpoint Kinase (Chk) | ||
A selective checkpoint kinase inhibitor | |||||
| GC10793 | TCS 2312 | 838823-31-7 | Chk | ||
checkpoint kinase 1 (chk1) inhibitor | |||||
| GC13543 | Poloxin | 321688-88-4 | PLK | ||
An inhibitor of the Plk1 polo-box domain | |||||
| GC11181 | Thiazovivin | 1226056-71-8 | ROCK | ||
Thiazovivin是一种选择性Rho相关激酶（ROCK）抑制剂。 | |||||
| GC62174 | ON1231320 | 1312471-39-8 | Apoptosis | ||
ON1231320 (7ao), an arylsulfonyl pyrido-pyrimidinone, is a highly specific inhibitor of polo like kinase 2 (PLK2). It also blocks tumor cell cycle progression in the G2/M phase in mitosis and causes apoptosis. | |||||
| GC14234 | PF-477736 | 952021-60-2 | Checkpoint Kinase (Chk) | ||
A selective inhibitor of checkpoint kinase 1 | |||||
| GC15437 | RKI-1447 | 1342278-01-6 | ROCK | ||
A ROCK1 and ROCK2 inhibitor | |||||
| GC12827 | SLx-2119 | 911417-87-3 | ROCK | ||
SLx-2119是一种高效的Rho kinase (ROCK) 2抑制剂，IC50值为105nM。 | |||||
| GC16097 | Chroman 1 | 1273579-40-0 | ROCK | ||
A ROCK2 inhibitor | |||||
| GC13928 | HMN-214 | 173529-46-9 | PLK | ||
A prodrug form of HMN-176 | |||||
| GC16030 | MK-1775 | 955365-80-7 | Wee1 | ||
MK-1775 是一种有效的选择性 Wee1 激酶小分子抑制剂，IC50 值为 5.2 nM。 | |||||
| GC15739 | CHIR-124 | 405168-58-3 | Other Apoptosis | ||
A selective Chk1 inhibitor | |||||
| GC11835 | Deferasirox | 201530-41-8 | Ferroptosis | ||
Deferasirox是一种具口服活性的铁螯合剂，用于治疗铁过载疾病。 | |||||
| GC15283 | AZ3146 | 1124329-14-1 | Mps1 | ||
A selective inhibitor of the spindle checkpoint kinase Mps1 | |||||
| GC11118 | KU 55933 | 587871-26-9 | Autophagy | ||
KU 55933是一种高效且特异的ATM激酶抑制剂，能够使人类肿瘤细胞对电离辐射和化疗药物更加敏感。KU 55933在体外的IC₅₀值为13nM，Ki值为2.2nM。 | |||||
| GC11511 | Vincristine sulfate | 2068-78-2 | Other Apoptosis | ||
An antimitotic inhibitor of tubulin polymerization | |||||
| GC10293 | VE-821 | 1232410-49-9 | ATM/ATR | ||
An inhibitor of ATR | |||||