关于 "nAChR" 的结果8 个结果
- Galanthamine HBrCAS: 1953-04-4
An alkaloid with AChE inhibitory and nAChR potentiating activities
AChR - Varenicline TartrateCAS: 375815-87-5
Varenicline Tartrate是一种选择性α7和α4β2烟碱型乙酰胆碱受体（nAChR）激动剂，对α4β2 nAChR的IC 50 值为250nM。
- Varenicline (CP 526555) dihydrochlorideCAS: 866823-63-4
Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.
AChR - α-Conotoxin GICAS: 76862-65-2
α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ.
AChR
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC14624 | Galanthamine HBr | 1953-04-4 | AChR | ||
An alkaloid with AChE inhibitory and nAChR potentiating activities | |||||
| GC10948 | Varenicline Tartrate | 375815-87-5 | nAChR | ||
Varenicline Tartrate是一种选择性α7和α4β2烟碱型乙酰胆碱受体（nAChR）激动剂，对α4β2 nAChR的IC50值为250nM。 | |||||
| GC11643 | PNU-120596 | 501925-31-1 | nAChR | ||
PNU-120596是α7神经元烟碱乙酰胆碱受体（α7nAChR）的正变构调节剂，EC50值为216nM。 | |||||
| GC12453 | Succinylcholine Chloride Dihydrate | 6101-15-1 | AChR | ||
An agonist of muscle-type nAChRs | |||||
| GC15014 | A-867744 | 1000279-69-5 | Autophagy | ||
A positive allosteric modulator of α7 nAChRs | |||||
| GC16573 | Galanthamine | 357-70-0 | AChE | ||
An alkaloid with AChE inhibitory and nAChR potentiating activities | |||||
| GC26032 | Varenicline (CP 526555) dihydrochloride | 866823-63-4 | AChR | ||
Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation. | |||||
| GC26093 | α-Conotoxin GI | 76862-65-2 | AChR | ||
α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ. | |||||