GlpBio

Varenicline (CP 526555) dihydrochloride

目录号: GC26032纯度: >98%同义词: Chantix, Champix,CP 526555 dihydrochloride
COASDSData Sheet
Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.
Varenicline (CP 526555) dihydrochloride
Cas No.: 866823-63-4
规格价格库存数量操作
5mg¥675.00现货
1
10mg¥1,080.00现货
1
25mg¥1,800.00现货
1
50mg¥3,150.00现货
1
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产品描述 Description

Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.

Varenicline induces dose-dependent and sustains increases in striatal DRD2/3 in rats, particularly in the ventral striatum.[2]

[1] Mihalak KB, et al. Mol Pharmacol. 2006 Sep;70(3):801-5. [2] Crunelle CL, et al. Eur Neuropsychopharmacol. 2011 Feb;21(2):205-10.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
866823-63-4
同义词
Chantix, Champix,CP 526555 dihydrochloride
分子式
C13H15Cl2N3
分子量
284.18 g/mol
溶解性
DMSO: 57 mg/mL (200.58 mM);Water: 57 mg/mL (200.58 mM);Ethanol: 29 mg/mL (102.05 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol