GlpBio

SC99

目录号: GC61269纯度: >98.50%
SC99 is an orally active, selective STAT3 inhibitor targeting JAK2-STAT3 pathway by docking into the ATP-binding pocket of JAK2, also inhibits phosphorylation of JAK2and STAT3 with no effects on the other kinases associated with STAT3 signaling.
SC99
Cas No.: 882290-02-0
规格价格库存数量操作
1mg¥335.00现货
1
5mg¥825.00现货
1
10mg¥1,243.00现货
1
25mg¥2,057.00现货
1
50mg¥2,884.00现货
1
100mg¥3,824.00现货
1
10mM (in 1mL DMSO)¥610.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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产品描述 Description

SC99 is an orally active, selective STAT3 inhibitor targeting JAK2-STAT3 pathway by docking into the ATP-binding pocket of JAK2, also inhibits phosphorylation of JAK2and STAT3 with no effects on the other kinases associated with STAT3 signaling.

[1] Zhang Z, et al. Oncotarget. 2016 Feb 23;7(8):9296-308. [2] Xu Z, et al. Acta Pharmacol Sin. 2017 May;38(5):651-659.

产品文档 Product Documents

Purity:>98.50%

化学性质Chemical Properties

CAS 号
882290-02-0
SMILES
N#C/C(C(C1=CC=C(Cl)C=C1)=O)=N\NC2=CC=C(F)C(Cl)=C2
分子式
C15H8Cl2FN3O
分子量
336.15 g/mol
溶解性
DMSO: 83.33 mg/mL (247.90 mM); Water: < 0.1 mg/mL (insoluble)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol