SB 297006

目录号: GC11946纯度: >99.50%
A selective antagonist of CCR3

SB 297006
Cas No.: 58816-69-6
规格价格库存数量操作
5mg¥665.00现货
1
10mg¥1,120.00现货
1
25mg¥1,890.00现货
1
50mg¥2,835.00现货
1
100mg¥4,200.00现货
1
10mM (in 1mL DMSO)¥732.00现货
1

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产品描述 Description

SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.

SB297006 is a CCR3 antagonist, significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells (NPCs) at 100 μM[1].

References:
[1]. Wang F, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017 Feb 7;8(1):26.

实验参考方法 Experimental Reference Method

Cell experiment:

To evaluate CCR3 blocking, neural progenitor cells (NPCs) are incubated with the CCR3 antagonist SB297006 (100 μM) for 30 minutes and then stimulated with CCL11 (2 μg/mL). After 3 days of culture, NPCs are subjected to CCK-8 assays[1].

References:

[1]. Wang F, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017 Feb 7;8(1):26.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
58816-69-6
化学名
(S,Z)-N-(1-ethoxy-3-(4-nitrophenyl)-1-oxopropan-2-yl)benzimidic acid
SMILES
CCOC([C@](/N=C(O)/C1=CC=CC=C1)([H])CC2=CC=C(N(=O)=O)C=C2)=O
分子式
C18H18N2O5
分子量
342.35 g/mol
溶解性
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol