Gutathione S-transferase
Gutathione S-transferase(谷胱甘肽S-转移酶)
GSTs (Glutathione s-transferases)is a detoxification enzyme that catalyze the binding of electrophilic substrates to glutathione. They involved in removal of ROS, inhibition of Jun kinase and can conjugate non-catalytically to various ligands.
Gutathione S-transferase 相关产品(13)
- GC10519Ethacrynic acid - d5CAS: 1330052-59-9
An internal standard for the quantification of ethacrynic acid
- GC18095EzatiostatCAS: 168682-53-9纯度: >98.00%
Ezatiostat是一种谷胱甘肽的三肽类似物、选择性的口服活性的谷胱甘肽S-转移酶P1-1（GSTP1）抑制剂。
- GC30647TLK117 (TER117)CAS: 152684-53-2纯度: >99.50%
TLK117 (TER117) 是 TLK199 的活性代谢物，选择性抑制谷胱甘肽 S-转移酶 P1-1 (GSTP1-1)，Ki 为 0.4 ⋼M 用于 GSTP。
- GC35727Coniferyl ferulateCAS: 63644-62-2纯度: >98.50%
A monolignal conjugate with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13409 | Ezatiostat hydrochloride | 286942-97-0 | - | |
An inhibitor of GSTP1-1 | ||||
| GC10519 | Ethacrynic acid - d5 | 1330052-59-9 | - | |
An internal standard for the quantification of ethacrynic acid | ||||
| GC17287 | Iberin | 505-44-2 | >98.00% | |
A natural isothiocyanate | ||||
| GC18095 | Ezatiostat | 168682-53-9 | >98.00% | |
Ezatiostat是一种谷胱甘肽的三肽类似物、选择性的口服活性的谷胱甘肽S-转移酶P1-1（GSTP1）抑制剂。 | ||||
| GC30647 | TLK117 (TER117) | 152684-53-2 | >99.50% | |
TLK117 (TER117) 是 TLK199 的活性代谢物，选择性抑制谷胱甘肽 S-转移酶 P1-1 (GSTP1-1)，Ki 为 0.4 ⋼M 用于 GSTP。 | ||||
| GC32971 | GSTO1-IN-1 | 568544-03-6 | >99.00% | |
GSTO1-IN-1是一种有效的谷胱甘肽S-转移酶omega1(GSTO1)抑制剂，IC50为31nM。 | ||||
| GC33342 | GSTO-IN-2 | 1202710-57-3 | >98.00% | |
GSTO-IN-2是一种谷胱甘肽S-转移酶(glutathioneS-transferase)抑制剂，对于GSTA2，GSTM1和GSTP1-1的IC50值分别为3.6，16.3，1.4μM。 | ||||
| GC35727 | Coniferyl ferulate | 63644-62-2 | >98.50% | |
A monolignal conjugate with diverse biological activities | ||||
| GC35759 | Curzerene | 17910-09-7 | - | |
Curzerene, a sesquiterpene isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity, inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression and induces cell apoptosis. | ||||
| GC44882 | Seneciphylline | 480-81-9 | >99.50% | |
An alkaloid with diverse biological activities | ||||
| GC63518 | LAS17 | 2362527-67-9 | - | |
LAS17 是一种强效的，不可逆的，选择性谷胱甘肽 S-转移酶 Pi (GSTP1) 抑制剂。LAS17 抑制 GSTP1 活性，IC50 为 0.5 µM. | ||||
| GC64919 | AZD9898 | 2042347-69-1 | - | |
AZD9898 是一种口服有效的白三烯-C4 合成酶 (LTC4S) 抑制剂，IC50 值为 0.28 nM。AZD9898 减轻GABA 结合和肝毒性信号。AZD9898 可用于哮喘的研究。 | ||||
| GC65438 | TK05 | 1245734-61-5 | - | |
TK05 是一种有效选择性的白三烯 C4 合成酶 (LTC4S) 抑制剂，其 IC50 值为 95 nM。 | ||||