PDE
PDE(磷酸二酯酶)
PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.
PDE 相关产品(241)
- GC19512Bay 60-7550CAS: 439083-90-6纯度: >98.00%
Bay 60-7550是一种高效磷酸二酯酶2(PDE2)抑制剂，对从牛心脏中纯化的PDE2的IC 50 值为2.0±0.7nM。
- GC25001(R)-AvanafilCAS: 1638497-26-3
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
- GC30390Autotaxin modulator 1CAS: 1548743-69-6纯度: >98.50%
Autotaxinmodulator1是出自专利WO2014018881A1中的新型Autotaxin调节剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13076 | Deltarasin | 1440898-61-2 | - | |
A KRAS inhibitor | ||||
| GC13275 | Ibudilast | 50847-11-5 | >99.50% | |
An inhibitor of PDE4 | ||||
| GC13444 | Doxofylline | 69975-86-6 | >99.00% | |
A bronchodilator | ||||
| GC13956 | 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide | 107522-19-0 | - | |
An inhibitor of PDE7 | ||||
| GC14180 | GSK256066 | 801312-28-7 | >98.50% | |
A potent PDE4 inhibitor | ||||
| GC14510 | PF-8380 | 1144035-53-9 | >99.00% | |
An inhibitor of autotaxin | ||||
| GC14697 | HA 130 | 1229652-21-4 | >99.00% | |
A reversible autotaxin inhibitor | ||||
| GC15037 | Sildenafil mesylate | 1308285-21-3 | - | |
A PDE5 inhibitor | ||||
| GC15242 | Vardenafil | 224785-90-4 | - | |
Vardenafil 是一种具有口服活性的选择性磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 0.7 nM。 | ||||
| GC16072 | ML-030 | 1013750-77-0 | >98.00% | |
A selective inhibitor of PDE4A | ||||
| GC16629 | Rolipram | 61413-54-5 | >99.50% | |
A phosphodiesterase-4 inhibitor | ||||
| GC16849 | MBCQ | 150450-53-6 | >99.00% | |
An inhibitor of PDE5 | ||||
| GC16856 | Avanafil | 330784-47-9 | >98.00% / >99.00% | |
A potent and selective PDE5 inhibitor | ||||
| GC17673 | Dipyridamole | 58-32-2 | >99.50% | |
A PDE5A inhibitor | ||||
| GC17685 | Sildenafil Citrate | 171599-83-0 | >99.50% | |
A PDE5 inhibitor | ||||
| GC19068 | BI-409306 | 1189767-28-9 | >99.00% | |
A potent and selective PDE9A inhibitor | ||||
| GC19111 | CP671305 | 445295-04-5 | >99.50% | |
A potent PDE4D inhibitor | ||||
| GC19168 | GLPG1690 | 1628260-79-6 | >99.50% | |
GLPG1690(Ziritaxestat) 是一种新型的autotaxin (ATX)抑制剂，IC 50 为131 nM, K i 为15 nM。它能有效阻止特发性肺纤维化的进展。 | ||||
| GC19314 | RVT-501 | 947620-48-6 | >98.00% | |
An inhibitor of PDE4 | ||||
| GC19343 | Balipodect | 1238697-26-1 | >98.50% | |
A potent inhibitor of PDE10A | ||||
| GC19512 | Bay 60-7550 | 439083-90-6 | >98.00% | |
Bay 60-7550是一种高效磷酸二酯酶2(PDE2)抑制剂，对从牛心脏中纯化的PDE2的IC 50 值为2.0±0.7nM。 | ||||
| GC25001 | (R)-Avanafil | 1638497-26-3 | - | |
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM. | ||||
| GC30390 | Autotaxin modulator 1 | 1548743-69-6 | >98.50% | |
Autotaxinmodulator1是出自专利WO2014018881A1中的新型Autotaxin调节剂。 | ||||
| GC30437 | ER21355 | 150452-18-9 | - | |
ER21355是一种磷酸二酯酶5(phosphodiesterase5)的抑制剂，用于治疗前列腺疾病。 | ||||