P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC41655(±)19(20)-EDP EthanolamideCAS: 2123485-34-5纯度: >98.00%
An ω-3 endocannabinoid epoxide and CB receptor agonist
- GC41656(±)2-(14,15-Epoxyeicosatrienoyl) GlycerolCAS: 848667-56-1纯度: >95.00%
A cytochrome P450 metabolite of 2-AG
- GC41660(±)4(5)-EpDPA methyl esterCAS: 121818-29-9纯度: >98.00%
Stable precursor of (±)4(5)-EpDPA, a CYP450 metabolite of DHA
- GC41720(R)-Omeprazole (sodium salt)CAS: 161796-77-6纯度: >98.00%
An inactive isomer of a gastric proton pump inhibitor
- GC4208520-hydroxy N-Arachidonoyl Taurine纯度: >95.00%
A potential CYP450 metabolite of N-arachidonoyl-taurine
- GC424024-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)纯度: >95.00%
An inactive metabolite of (S)-duloxetine
- GC424094-hydroxy Nebivolol (hydrochloride)CAS: 2717115-85-8纯度: >98.00%
A major metabolite of nebivolol
- GC425515-hydroxymethyl Tolterodine (formate)CAS: 380636-49-7纯度: >98.00%
An active metabolite of tolterodine and fesoterodine
- GC425806-hydroxy ChlorzoxazoneCAS: 1750-45-4纯度: >97.00%
6-hydroxy Chlorzoxazone是Chlorzoxazone在体内的主要代谢产物。6-hydroxy Chlorzoxazone主要通过肝脏细胞色素P450酶系统形成，在生化研究中常作为探针用于定量评估CYP2E1的活性。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC41653 | (±)16(17)-DiHDPA | 1345275-27-5 | >95.00% | |
An epoxygenase metabolite of DHA | ||||
| GC41654 | (±)19(20)-DiHDPA | - | >98.00% | |
An epoxygenase metabolite of DHA | ||||
| GC41655 | (±)19(20)-EDP Ethanolamide | 2123485-34-5 | >98.00% | |
An ω-3 endocannabinoid epoxide and CB receptor agonist | ||||
| GC41656 | (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol | 848667-56-1 | >95.00% | |
A cytochrome P450 metabolite of 2-AG | ||||
| GC41660 | (±)4(5)-EpDPA methyl ester | 121818-29-9 | >98.00% | |
Stable precursor of (±)4(5)-EpDPA, a CYP450 metabolite of DHA | ||||
| GC41662 | (±)5(6)-EET Ethanolamide | - | >95.00% | |
A potential cytochrome P450 metabolite of AEA | ||||
| GC41663 | (±)7(8)-DiHDPA | 168111-93-1 | >98.00% | |
A major metabolite of DHA | ||||
| GC41665 | (±)8(9)-EET Ethanolamide | - | >98.00% | |
A cytochrome P450 metabolite of AEA | ||||
| GC41694 | (3S)-hydroxy Quinidine | 53467-23-5 | >98.00% | |
An active quinidine metabolite | ||||
| GC41720 | (R)-Omeprazole (sodium salt) | 161796-77-6 | >98.00% | |
An inactive isomer of a gastric proton pump inhibitor | ||||
| GC41837 | 1,3,7-Trimethyluric Acid | 5415-44-1 | >98.00% | |
A metabolite of caffeine | ||||
| GC41945 | 16-hydroxy Hexadecanoic Acid | 506-13-8 | >98.00% | |
CYP450 metabolite of palmitic acid | ||||
| GC42083 | 20-HETE Ethanolamide | 942069-11-6 | >98.00% | |
A putative CYP450 metabolite of AEA | ||||
| GC42085 | 20-hydroxy N-Arachidonoyl Taurine | - | >95.00% | |
A potential CYP450 metabolite of N-arachidonoyl-taurine | ||||
| GC42402 | 4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt) | - | >95.00% | |
An inactive metabolite of (S)-duloxetine | ||||
| GC42405 | 4-hydroxy Atorvastatin (calcium salt) | 265989-44-4 | >90.00% | |
A metabolite of atorvastatin | ||||
| GC42409 | 4-hydroxy Nebivolol (hydrochloride) | 2717115-85-8 | >98.00% | |
A major metabolite of nebivolol | ||||
| GC42546 | 5-hydroxy Diclofenac | 69002-84-2 | >98.00% | |
An active metabolite of diclofenac | ||||
| GC42550 | 5-hydroxy-6-methoxy (S)-Duloxetine | 741693-79-8 | >95.00% | |
A metabolite of (S)-duloxetine | ||||
| GC42551 | 5-hydroxymethyl Tolterodine (formate) | 380636-49-7 | >98.00% | |
An active metabolite of tolterodine and fesoterodine | ||||
| GC42580 | 6-hydroxy Chlorzoxazone | 1750-45-4 | >97.00% | |
6-hydroxy Chlorzoxazone是Chlorzoxazone在体内的主要代谢产物。6-hydroxy Chlorzoxazone主要通过肝脏细胞色素P450酶系统形成，在生化研究中常作为探针用于定量评估CYP2E1的活性。 | ||||
| GC42584 | 6-O-desmethyl Donepezil | 120013-56-1 | >98.00% | |
An active metabolite of donepezil | ||||
| GC42586 | 6α-hydroxy Paclitaxel | 153212-75-0 | >95.00% | |
A metabolite of paclitaxel | ||||
| GC42626 | 8-hydroxy Efavirenz | 205754-33-2 | >98.00% | |
A major metabolite of efavirenz | ||||