P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC491592-(1-Piperazinyl)pyrimidineCAS: 20980-22-7纯度: >98.00%
An α 2 -AR antagonist and active metabolite of azapirones
- GC491693,8’-BiapigeninCAS: 101140-06-1纯度: >98.00%
A biflavonoid with diverse biological activities
- GC49189(E/Z)-4-hydroxy Tamoxifen-d5CAS: 2470232-57-4纯度: >99.00%
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
- GC49195Indapamide-13C-d3CAS: 2934053-07-1纯度: >99.00%
An internal standard for the quantification of indapamide
- GC49291rac-N-desmethyl Ivabradine-d6 (hydrochloride)CAS: 2804269-05-2纯度: >99.00%
An internal standard for the quantification of N-desmethyl ivabradine
- GC493207-Ethoxy-4-(trifluoromethyl)coumarinCAS: 115453-82-2纯度: >95.00%
A fluorogenic substrate for CYPs
- GC49355Norfluoxetine-d5 (hydrochloride)CAS: 1185132-92-6纯度: >99.00%
An internal standard for the quantification of norfluoxetine
- GC493622-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxalineCAS: 77500-04-0纯度: >95.00%
A food-derived carcinogen
- GC49399N-Desbutyl Dronedarone (hydrochloride)CAS: 197431-02-0纯度: >95.00%
An active metabolite of dronedarone
- GC49421Atorvastatin lactone-d5CAS: 125995-03-1纯度: >99.00%
An internal standard for the quantification of atorvastatin lactone
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC49146 | Colupulone | 468-27-9 | >95.00% | |
A β-acid with diverse biological activities | ||||
| GC49159 | 2-(1-Piperazinyl)pyrimidine | 20980-22-7 | >98.00% | |
An α 2 -AR antagonist and active metabolite of azapirones | ||||
| GC49169 | 3,8’-Biapigenin | 101140-06-1 | >98.00% | |
A biflavonoid with diverse biological activities | ||||
| GC49185 | Mirtazapine N-oxide | 155172-12-6 | >95.00% | |
A metabolite of mirtazapine | ||||
| GC49189 | (E/Z)-4-hydroxy Tamoxifen-d5 | 2470232-57-4 | >99.00% | |
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen | ||||
| GC49195 | Indapamide-13C-d3 | 2934053-07-1 | >99.00% | |
An internal standard for the quantification of indapamide | ||||
| GC49202 | Desmethyl Mirtazapine (hydrochloride) | 1188265-41-9 | >98.00% | |
A metabolite of mirtazapine | ||||
| GC49212 | trans-carboxy Glimepiride | 1217739-04-2 | >95.00% | |
A metabolite of glimepiride | ||||
| GC49230 | Ferroprotoporphyrin | 14875-96-8 | >95.00% | |
Ferroprotoporphyrin是血红蛋白中血红素的亚铁形式。 | ||||
| GC49281 | SPA70 | 931314-31-7 | >98.00% | |
A PXR antagonist | ||||
| GC49288 | Dolutegravir M1 | 1485081-26-2 | >95.00% | |
A metabolite of dolutegravir | ||||
| GC49291 | rac-N-desmethyl Ivabradine-d6 (hydrochloride) | 2804269-05-2 | >99.00% | |
An internal standard for the quantification of N-desmethyl ivabradine | ||||
| GC49320 | 7-Ethoxy-4-(trifluoromethyl)coumarin | 115453-82-2 | >95.00% | |
A fluorogenic substrate for CYPs | ||||
| GC49355 | Norfluoxetine-d5 (hydrochloride) | 1185132-92-6 | >99.00% | |
An internal standard for the quantification of norfluoxetine | ||||
| GC49362 | 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline | 77500-04-0 | >95.00% | |
A food-derived carcinogen | ||||
| GC49399 | N-Desbutyl Dronedarone (hydrochloride) | 197431-02-0 | >95.00% | |
An active metabolite of dronedarone | ||||
| GC49403 | Benzarone | 1477-19-6 | >98.00% | |
An active metabolite of benzbromarone | ||||
| GC49409 | Desmethyl Ranolazine | 172430-45-4 | >95.00% | |
A metabolite of ranolazine | ||||
| GC49410 | CVT-2738 | 5294-61-1 | >98.00% | |
An active metabolite of ranolazine | ||||
| GC49421 | Atorvastatin lactone-d5 | 125995-03-1 | >99.00% | |
An internal standard for the quantification of atorvastatin lactone | ||||
| GC49429 | 6-keto Lithocholic Acid | 2393-61-5 | >95.00% | |
A metabolite of lithocholic acid | ||||
| GC49501 | Nirvanol | 631-07-2 | >98.00% | |
An active metabolite of mephenytoin | ||||
| GC49503 | Thujopsene | 470-40-6 | >85.00% | |
A sesquiterpene with diverse biological activities | ||||
| GC49544 | 8-hydroxy Mirtazapine | 102335-57-9 | >95.00% | |
A metabolite of mirtazapine | ||||