Dehydrogenase
Dehydrogenase(脱氢酶)
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
Dehydrogenase 相关产品(39)
- GC25039AG-120 (racemic)CAS: 1448346-63-1
AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity.
- GC25389Ethyl potassium malonateCAS: 6148-64-7
Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
- GC50508PKUMDL WQ 2101CAS: 304481-72-9
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
- GC50509PKUMDL WQ 2201CAS: 592474-91-4
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH)
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC15738 | BVT 2733 | 376640-41-4 | >98.00% | |
An 11β-HSD1 inhibitor | ||||
| GC15943 | NCT-503 | 1916571-90-8 | >98.00% | |
NCT-503 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂，IC50 为 2.5 μM用 NCT-503 处理三种 PHGDH 非依赖性细胞系和五种 PHGDH 依赖性细胞系表明，NCT-503 对 PHGDH 依赖性细胞系的 EC50 值为 8-16 μM，并且对其他 PHGDH 非依赖性细胞无毒性 行。 | ||||
| GC16597 | Alda 1 | 349438-38-6 | >99.50% | |
Alda 1是一种醛脱氢酶2（ALDH2）激活剂。 | ||||
| GC16816 | Galloflavin | 568-80-9 | - | |
An inhibitor of lactate dehydrogenase | ||||
| GC16860 | NCT-502 | 1542213-00-2 | >99.00% | |
A PHGDH inhibitor | ||||
| GC16951 | Stiripentol | 49763-96-4 | >99.50% | |
An antiepileptic compound | ||||
| GC17293 | PHGDH-inactive | 1914971-16-6 | >99.50% | |
A negative control for NCT-502 and NCT-503 | ||||
| GC17914 | Fomepizole | 7554-65-6 | >99.50% | |
An alcohol dehydrogenase inhibitor | ||||
| GC25039 | AG-120 (racemic) | 1448346-63-1 | - | |
AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. | ||||
| GC25389 | Ethyl potassium malonate | 6148-64-7 | - | |
Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate. | ||||
| GC50508 | PKUMDL WQ 2101 | 304481-72-9 | - | |
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH) | ||||
| GC50509 | PKUMDL WQ 2201 | 592474-91-4 | - | |
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH) | ||||
| GP26164 | LDHA, E.Coli Active | - | - | |
LDHA E | ||||
| GP26169 | NQO1 Human, Active | - | - | |
NQO1 Human Recombinant produced in E | ||||
| GP26172 | PGD Human, Active | - | - | |
PGD Human Recombinant produced in E | ||||