GlpBio

GABA Receptor

GABA Receptor(γ-氨基丁酸受体)

GABA receptors are a class of receptors that respond to the GABA (neurotransmitter gamma-aminobutyric acid), the chief inhibitory neurotransmitter in the vertebrate central nervous system.

GABA Receptor 相关产品(154)

  • GC30827 structure
    GC30827Pipequaline (PK-8165)
    CAS: 77472-98-1
    纯度: >99.50%

    A partial agonist of central benzodiazepine receptors

  • GC30844 structure
    GC30844Afloqualone
    CAS: 56287-74-2
    纯度: >98.00%

    An Analytical Reference Standard

  • GC30862 structure
    GC30862L-Cycloserine ((S)-4-Amino-3-isoxazolidone)
    CAS: 339-72-0
    纯度: >99.00%

    An inhibitor of sphingolipid synthesis and aminotransferases

  • GC30865 structure
    GC30865TPA 023
    CAS: 252977-51-8
    纯度: >99.50%

    TPA023是GABAAα2/α3的选择性的激动剂，Ki值为0.19-0.41nM。

  • GC30889 structure
    GC30889(-)-Securinine
    CAS: 5610-40-2
    纯度: >98.00%

    An alkaloid

  • GC30898 structure
    GC308986-Methylflavone
    CAS: 29976-75-8
    纯度: >98.00%

    6-methylflavone是α1β2γ2L和α1β2GABAA受体的激活剂。

  • GC30930 structure
    GC30930DAA-1106
    CAS: 220551-92-8
    纯度: >99.50%

    A TSPO agonist

  • GC30933 structure
    GC30933(+)-Kavain
    CAS: 500-64-1
    纯度: >98.00%

    A kavalactone with diverse biological activities

  • GC30943 structure
    GC309436,2'-Dihydroxyflavone
    CAS: 92439-20-8
    纯度: >99.50% / >98.00%

    6,2'-Dihydroxyflavone是一个新型的GABAA受体拮抗剂。

  • GC30983 structure
    GC30983alpha-Asarone (α-Asarone)
    CAS: 2883-98-9
    纯度: >99.50%

    An inhibitor of HMG- CoA reductase and CYP450 isoforms

  • GC31010 structure
    GC31010AZD-6280
    CAS: 942436-93-3
    纯度: >99.00%

    AZD-6280 is a selective GABAA (α2/3) receptor modulator, used for treatment of generalized anxiety disorder.

  • GC31013 structure
    GC31013U-101017 (PNU 101017)
    CAS: 170568-47-5

    U-101017 (PNU 101017) 是苯二氮卓受体和 GABAA 受体的部分激动剂，具有抗焦虑作用。

  • GC31018 structure
    GC31018NEO 376 (SPI-376)
    CAS: 496921-73-4

    NEO 376 (SPI-376) 是 5-HT1 受体、GABA 受体和多巴胺受体的选择性调节剂，具有抗精神病活性。

  • GC31023 structure
    GC31023Ethyl dirazepate
    CAS: 23980-14-5

    Ethyldirazepate是一种苯并二氮杂(benzodiazepine)衍生物。具有抗焦虑和催眠特性。

  • GC31049 structure
    GC31049RWJ-51204
    CAS: 205701-85-5

    RWJ-51204是GABA(A)receptor的部分激动剂，Ki值为0.2-2nM。

  • GC31052 structure
    GC31052CP-409092
    CAS: 194098-25-4

    CP-409092是GABA(A)的部分激动剂，主要用于抗焦虑研究。

  • GC31112 structure
    GC31112Sarmazenil (Ro 15-3505)
    CAS: 78771-13-8

    Sarmazenil (Ro 15-3505) 是一种苯二氮卓受体拮抗剂。

  • GC31120 structure
    GC31120Cirsimaritin
    CAS: 6601-62-3
    纯度: >98.00%

    Cirsimaritin是一种存在于植物中的二甲氧基黄酮，具有抗癌潜力，并显示出显著的抗菌、抗氧化、解痉作用，同时还可抑制环氧合酶-1。

  • GC31121 structure
    GC31121S-8510 phosphate (SB-737552 phosphate)
    CAS: 151466-23-8

    S-8510 (phosphate) 是一种反向苯二氮卓 (BDZ) 受体激动剂，对 -GABA 和 +GABA 的 Kis 分别为 34.6 nM、36.2 nM。

  • GC31142 structure
    GC31142Uldazepam (U31920)
    CAS: 28546-58-9

    Uldazepam (U31920) 是一种苯二氮卓类衍生物，具有治疗焦虑症的潜力。

  • GC31196 structure
    GC31196SX-3228
    CAS: 156364-04-4

    SX-3228是一种选择性苯二氮卓类(benzodiazepine1，BZ1)受体激动剂，IC50为17nM。

  • GC31224 structure
    GC31224Carburazepam (RGH 3331)
    CAS: 59009-93-7

    Carburazepam (RGH 3331) 是一种衍生自苯二氮卓类药物的药物。

  • GC31257 structure
    GC31257Rilmazafone hydrochloride (450191S)
    CAS: 85815-37-8
    纯度: >99.50%

    Rilmazafone hydrochloride (450191S) (450191S) 是苯二氮卓 (omega) 配体。

  • GC31282 structure
    GC31282p-Hydroxybenzaldehyde
    CAS: 123-08-0

    p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.