GlpBio

AChE

AChE(乙酰胆碱脂酶)

AChE, also know as acetylcholinesterase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine.

AChE 相关产品(100)

  • GC18207 structure
    GC18207Pitofenone (hydrochloride)
    CAS: 1248-42-6
    纯度: >99.50%

    An antispasmodic agent

  • GC18891 structure
    GC18891Malathion
    CAS: 121-75-5
    纯度: >98.00%

    An organophosphate insecticide

  • GC30290 structure
    GC30290Neostigmine methyl sulfate
    CAS: 51-60-5
    纯度: >99.50%

    A reversible acetylcholinesterase inhibitor

  • GC30446 structure
    GC30446MHP 133
    CAS: 147340-43-0

    MHP133是一种多靶点抑制剂，可以抑制AChE的活性，KKi值为69μM;同时抑制毒蕈碱M1和M2受体，5HT4受体和咪唑I2受体。

  • GC30810 structure
    GC30810Donepezil (E2020)
    CAS: 120014-06-4
    纯度: >99.50%

    Donepezil (E2020)是一种乙酰胆碱酯酶（AChE）抑制剂，IC50为6.7nM。

  • GC30856 structure
    GC30856Protriptyline hydrochloride
    CAS: 1225-55-4
    纯度: >99.50%

    A tricyclic antidepressant

  • GC30908 structure
    GC30908Drofenine hydrochloride (Hexahydroadiphenine hydrochloride)
    CAS: 548-66-3
    纯度: >98.00%

    Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.

  • GC31044 structure
    GC31044T 82
    CAS: 252264-92-9

    T82是一种有效的5-HT3拮抗剂和乙酰胆碱酯酶(AChE)的抑制剂，用于阿尔茨海默症的研究。

  • GC31190 structure
    GC31190Demecarium Bromide (BC-48)
    CAS: 56-94-0

    Demecarium Bromide (BC-48) (BC-48) 是一种有效的胆碱酯酶抑制剂，表观亲和力 (Kiapp) 为 0.15 μM.

  • GC31193 structure
    GC31193Benactyzine hydrochloride
    CAS: 57-37-4
    纯度: >99.50%

    Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.

  • GC31699 structure
    GC31699Scopoletin (Gelseminic acid)
    CAS: 92-61-5
    纯度: >98.00%

    A natural coumarin

  • GC32194 structure
    GC32194Metrifonate (Trichlorfon)
    CAS: 52-68-6
    纯度: >98.50%

    Metrifonate是一种不可逆的有机磷乙酰胆碱酯酶抑制剂,用作杀虫剂,控制苍蝇和蟑螂。

  • GC33067 structure
    GC33067Sophoflavescenol
    CAS: 216450-65-6
    纯度: >98.00%

    Sophoflavescenol是一种异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50值为0.013μM；同时抑制RLAR，HRAR，BACE1，AChE和BChE，IC50值分别为0.30µM，0.17µM，10.98µM，8.37µM和8.21µM。

  • GC33684 structure
    GC33684Pralidoxime chloride (2-PAM chloride)
    CAS: 51-15-0
    纯度: >99.00%

    An AChE reactivator

  • GC34288 structure
    GC34288Pyridostigmine D6 bromide
    纯度: >99.00%

    PyridostigmineD6bromide是Pyridostigmine的氘代化合物标准品。

  • GC34947 structure
    GC34947(-)-Corynoxidine
    CAS: 57906-85-1

    (-)-Corynoxidine 分离自延胡索 Corydalis speciosa，是一种乙酰胆碱酯酶 acetylcholinesterase 抑制剂，IC50 值为 89.0 μM。(-)-Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌菌株有不同程度的抗菌活性。

  • GC34993 structure
    GC34993(R)-Rivastigmine D6 tartrate
    CAS: 194930-00-2

    An internal standard for the quantification of rivastigmine

  • GC35236 structure
    GC35236Acetylshikonin
    CAS: 24502-78-1
    纯度: >98.00%

    Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。

  • GC35272 structure
    GC35272Ajmalicine
    CAS: 483-04-5

    A terpenoid indole alkaloid

  • GC35279 structure
    GC35279Aldicarb sulfone
    CAS: 1646-88-4
    纯度: >99.00%

    A metabolite of aldicarb

  • GC35564 structure
    GC35564BuChE-IN-TM-10
    CAS: 2313524-95-5

    BuChE-IN-TM-10 (TM-10)是一种有效的丁基胆碱酯酶 (BuChE) 抑制剂，其IC50 值为8.9 nM。BuChE inhibitor 1能够抑制和分解自诱导的Aβ聚合, 表现出强大的抗氧化活性和良好的血脑屏障 (BBB) 渗透性。有治疗阿尔兹海默症的潜能。

  • GC35996 structure
    GC35996Epiberberine chloride
    CAS: 889665-86-5
    纯度: >99.50%

    An alkaloid with diverse biological activities

  • GC36103 structure
    GC36103Galanthamine hydrobromide
    CAS: 1953-04-4
    纯度: >98.00%

    Galanthamine氢溴酸盐是长效的中心活性的乙酰胆碱酯酶（AChE）抑制剂，IC50为410 nM，同时是神经元烟碱乙酰胆碱受体的变构增强剂。

  • GC36104 structure
    GC36104Galanthaminone
    CAS: 510-77-0
    纯度: >99.50%

    Galanthaminone是竞争性可逆的胆碱酯酶（AChE）抑制剂，可作用于多种记忆障碍疾病。