GlpBio

5-HT Receptor

5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

5-HT Receptor 相关产品(419)

  • GC36501 structure
    GC36501LY 344864 hydrochloride
    CAS: 1217756-94-9

    A 5-HT 1F receptor antagonist

  • GC36502 structure
    GC36502LY 344864 racemate
    CAS: 186543-64-6
    纯度: >98.50%

    LY 344864 racemate 是一种 5-HT1F 受体激动剂, 来自专利 US 5708187 A。

  • GC36503 structure
    GC36503LY 344864 S-enantiomer
    CAS: 186544-27-4
    纯度: >99.50%

    LY 344864 S-enantiomer 是 LY344864 的 S 型对映体。LY344864 是 5-HT1F 受体激动剂。

  • GC36511 structure
    GC36511LY334370
    CAS: 182563-08-2
    纯度: >99.50%

    A 5-HT 1F receptor agonist

  • GC36548 structure
    GC36548Masupirdine free base
    CAS: 701205-60-9

    Masupirdine free base (SUVN-502 free base) 是一种有效的，选择性的，具有口服生物可利用且可穿透脑屏障的5-HT6 受体拮抗剂 (对人 5-HT6 受体的 Ki 为 2.04 nM)。Masupirdine free base (SUVN-502 free base) 对 5-HT2A 受体和其他 100个 靶点显示高选择性，有治疗阿尔茨海默病的潜力。

  • GC36693 structure
    GC36693Naratriptan D3 Hydrochloride
    CAS: 1190021-64-7

    Naratriptan D3盐酸盐是Naratriptan的氘代化合物标准品。

  • GC36844 structure
    GC36844Palonosetron
    CAS: 135729-61-2

    Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

  • GC36875 structure
    GC36875Perphenazine D8 Dihydrochloride

    Perphenazine D8二盐酸盐是Perphenazine氘代化合物标准品。

  • GC36912 structure
    GC36912Piboserod hydrochloride
    CAS: 178273-87-5

    Piboserod (SB 207266)盐酸盐是5-羟色胺受体5-HT4选择性抑制剂。

  • GC36919 structure
    GC36919Pimavanserin tartrate
    CAS: 706782-28-7
    纯度: >98.00%

    A 5-HT 2A inverse agonist

  • GC36924 structure
    GC36924Pipamperone
    CAS: 1893-33-0
    纯度: >99.50%

    Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 5-HT2A 受体 (pKi=8.2) 和 D4 受体 (pKi=8.0) 的高亲和力拮抗剂。Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 D2 受体 (pKi=6.7) 的低亲和力拮抗剂。

  • GC37055 structure
    GC37055Quetiapine D4 fumarate
    CAS: 1287376-15-1

    Quetiapine D4富马酸盐是Quetiapine氘代化合物标准品。

  • GC37539 structure
    GC37539Risperidone hydrochloride
    CAS: 666179-74-4

    An atypical antipsychotic

  • GC37540 structure
    GC37540Risperidone mesylate
    CAS: 666179-96-0

    An atypical antipsychotic

  • GC37569 structure
    GC37569RU 24969
    CAS: 66611-26-5
    纯度: >99.50% / >98.00%

    RU 24969是一种广泛使用的非选择性5-HT 1B/1A 激动剂，其对5-HT 1B 受体的Ki值为0.38nM，对5-HT 1A 受体的Ki值为2.5nM，而对大脑中的其他受体位点亲和力较低。

  • GC37596 structure
    GC37596SB 258719
    CAS: 195199-95-2
    纯度: >99.00%

    SB 258719 是一个有选择性的 5-HT7 受体拮抗剂，其 pKi 值为 7.5。

  • GC37597 structure
    GC37597SB 271046 Hydrochloride
    CAS: 209481-24-3
    纯度: >99.00%

    An orally-available 5-HT 6 antagonist

  • GC37599 structure
    GC37599SB-269970
    CAS: 201038-74-6
    纯度: >98.00%

    SB-269970是一种强效且选择性的5-HT 7 受体拮抗剂，具有高亲和力 (pK i = 8.9)。

  • GC37734 structure
    GC37734Tandospirone citrate
    CAS: 112457-95-1
    纯度: >98.50%

    Tandospirone (SM-3997), a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM, has anxiolytic and antidepressant activities.

  • GC37861 structure
    GC37861Urapidil
    CAS: 34661-75-1
    纯度: >98.00%

    An α 1 -AR antagonist and 5-HT 1A receptor partial agonist

  • GC37906 structure
    GC37906Vilazodone D8
    CAS: 1794789-93-7

    An internal standard for the quantification of vilazodone

  • GC37969 structure
    GC37969Ziprasidone D8
    CAS: 1126745-58-1

    An internal standard for the quantification of ziprasidone

  • GC38108 structure
    GC381082-Methyl-5-HT
    CAS: 78263-90-8
    纯度: >98.00% / >95.00%

    2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) 是一种有效的选择性 5-HT3 受体激动剂。2-Methyl-5-HT 显示出抗抑郁样作用。

  • GC38227 structure
    GC38227Gamma-Mangostin
    CAS: 31271-07-5
    纯度: >99.50%

    A xanthone with diverse biological activities